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LRRFIP2 LRR binding FLII interacting protein 2 [ Homo sapiens (human) ]

Gene ID: 9209, updated on 23-Nov-2021

Summary

Official Symbol
LRRFIP2provided by HGNC
Official Full Name
LRR binding FLII interacting protein 2provided by HGNC
Primary source
HGNC:HGNC:6703
See related
Ensembl:ENSG00000093167 MIM:614043
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HUFI-2
Summary
The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like protein FAT10 prevents the interaction of the encoded protein and TLR4, thereby inactivating the nuclear factor kappa B signaling pathway. In addition, this protein can downregulate the NLRP3 inflammasome by recruiting the caspase-1 inhibitor Flightless-I to the inflammasome complex. [provided by RefSeq, Jan 2017]
Expression
Ubiquitous expression in testis (RPKM 17.9), heart (RPKM 16.5) and 25 other tissues See more
Orthologs
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Genomic context

See LRRFIP2 in Genome Data Viewer
Location:
3p22.2
Exon count:
34
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (37052626..37176817, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (37094117..37217851, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene EPM2A interacting protein 1 Neighboring gene mutL homolog 1 Neighboring gene ribosomal protein L29 pseudogene 11 Neighboring gene RNA, U6 small nuclear 1301, pseudogene Neighboring gene ubiquitin conjugating enzyme E2 D3 pseudogene 2 Neighboring gene UBE2F pseudogene 1 Neighboring gene translation initiation factor IF-2-like Neighboring gene uncharacterized LOC105377642 Neighboring gene ribosomal protein S16 pseudogene 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20248, FLJ22683, FLJ58304, DKFZp434H2035

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables LRR domain binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in biological_process ND
No biological Data available
more info
 
involved_in regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
leucine-rich repeat flightless-interacting protein 2
Names
LRR FLII-interacting protein 2
leucine rich repeat (in FLII) interacting protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_053016.1 RefSeqGene

    Range
    7236..129192
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001134369.2NP_001127841.1  leucine-rich repeat flightless-interacting protein 2 isoform k

    See identical proteins and their annotated locations for NP_001127841.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) has a longer 5' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (k, also known as 3) is shorter, compared to isoform a.
    Source sequence(s)
    AK024692, BC017703, DC336346, R27776
    Consensus CDS
    CCDS46791.1
    UniProtKB/Swiss-Prot
    Q9Y608
    Related
    ENSP00000416364.2, ENST00000421276.6
    Conserved Domains (2) summary
    pfam04111
    Location:329424
    APG6; Autophagy protein Apg6
    pfam09738
    Location:47349
    LRRFIP; LRRFIP family
  2. NM_001282691.1NP_001269620.1  leucine-rich repeat flightless-interacting protein 2 isoform d

    See identical proteins and their annotated locations for NP_001269620.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) has a longer 5' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (d, also known as 4) is shorter, compared to isoform a.
    Source sequence(s)
    AK024692, AK302282, DB033703, R27776
    Consensus CDS
    CCDS63592.1
    UniProtKB/Swiss-Prot
    Q9Y608
    Related
    ENSP00000379705.2, ENST00000396428.6
    Conserved Domains (1) summary
    pfam09738
    Location:130428
    DUF2051; Double stranded RNA binding protein (DUF2051)
  3. NM_001348297.1NP_001335226.1  leucine-rich repeat flightless-interacting protein 2 isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) has a longer 5' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (b) is shorter, compared to isoform a.
    Source sequence(s)
    AC006583, AC126118
    Conserved Domains (2) summary
    pfam04111
    Location:525620
    APG6; Autophagy protein Apg6
    pfam09738
    Location:246545
    LRRFIP; LRRFIP family
  4. NM_001348298.1NP_001335227.1  leucine-rich repeat flightless-interacting protein 2 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) has a longer 5' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (c) is shorter, compared to isoform a.
    Source sequence(s)
    AC006583, AC126118
    Conserved Domains (2) summary
    pfam04111
    Location:455550
    APG6; Autophagy protein Apg6
    pfam09738
    Location:152475
    LRRFIP; LRRFIP family
  5. NM_001348299.1NP_001335228.1  leucine-rich repeat flightless-interacting protein 2 isoform e

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) has a longer 5' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (e) is shorter, compared to isoform a. Variants 7 and 8 both encode the same isoform (e).
    Source sequence(s)
    AC006583, AC126118
    Conserved Domains (2) summary
    pfam04111
    Location:397492
    APG6; Autophagy protein Apg6
    pfam09738
    Location:47417
    LRRFIP; LRRFIP family
  6. NM_001348300.1NP_001335229.1  leucine-rich repeat flightless-interacting protein 2 isoform e

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) has a longer 5' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (e) is shorter, compared to isoform a. Variants 7 and 8 both encode the same isoform (e).
    Source sequence(s)
    AC006583, AC126118
    Conserved Domains (2) summary
    pfam04111
    Location:397492
    APG6; Autophagy protein Apg6
    pfam09738
    Location:47417
    LRRFIP; LRRFIP family
  7. NM_001348301.1NP_001335230.1  leucine-rich repeat flightless-interacting protein 2 isoform f

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) has a longer 5' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (f) is shorter, compared to isoform a. Variants 9 and 10 both encode the same isoform (f).
    Source sequence(s)
    AC006583, AC126118
    Conserved Domains (2) summary
    pfam09738
    Location:47414
    LRRFIP; LRRFIP family
    cl25732
    Location:187488
    SMC_N; RecF/RecN/SMC N terminal domain
  8. NM_001348302.1NP_001335231.1  leucine-rich repeat flightless-interacting protein 2 isoform f

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10) has a longer 5' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (f) is shorter, compared to isoform a. Variants 9 and 10 both encode the same isoform (f).
    Source sequence(s)
    AC006583, AC126118
    Conserved Domains (2) summary
    pfam09738
    Location:47414
    LRRFIP; LRRFIP family
    cl25732
    Location:187488
    SMC_N; RecF/RecN/SMC N terminal domain
  9. NM_001348303.1NP_001335232.1  leucine-rich repeat flightless-interacting protein 2 isoform g

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11) has a longer 5' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (g) is shorter, compared to isoform a.
    Source sequence(s)
    AC006583, AC126118
    Conserved Domains (2) summary
    pfam04111
    Location:373468
    APG6; Autophagy protein Apg6
    pfam09738
    Location:47393
    LRRFIP; LRRFIP family
  10. NM_001348304.1NP_001335233.1  leucine-rich repeat flightless-interacting protein 2 isoform h

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12) has a longer 5' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (h) is shorter, compared to isoform a.
    Source sequence(s)
    AC006583, AC126118
    Conserved Domains (2) summary
    pfam04111
    Location:370465
    APG6; Autophagy protein Apg6
    pfam09738
    Location:47390
    LRRFIP; LRRFIP family
  11. NM_001348305.1NP_001335234.1  leucine-rich repeat flightless-interacting protein 2 isoform i

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13) has a longer 5' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (i) is shorter, compared to isoform a. Variants 13, 14, and 15 all encode the same isoform (i).
    Source sequence(s)
    AC006583, AC126118
    Conserved Domains (2) summary
    pfam04111
    Location:363458
    APG6; Autophagy protein Apg6
    pfam09738
    Location:47383
    LRRFIP; LRRFIP family
  12. NM_001348306.1NP_001335235.1  leucine-rich repeat flightless-interacting protein 2 isoform i

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14) has a longer 5' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (i) is shorter, compared to isoform a. Variants 13, 14, and 15 all encode the same isoform (i).
    Source sequence(s)
    AC006583, AC126118
    Conserved Domains (2) summary
    pfam04111
    Location:363458
    APG6; Autophagy protein Apg6
    pfam09738
    Location:47383
    LRRFIP; LRRFIP family
  13. NM_001348307.1NP_001335236.1  leucine-rich repeat flightless-interacting protein 2 isoform i

    Status: REVIEWED

    Description
    Transcript Variant: This variant (15) has a longer 5' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (i) is shorter, compared to isoform a. Variants 13, 14, and 15 all encode the same isoform (i).
    Source sequence(s)
    AC006583, AC126118
    Conserved Domains (2) summary
    pfam04111
    Location:363458
    APG6; Autophagy protein Apg6
    pfam09738
    Location:47383
    LRRFIP; LRRFIP family
  14. NM_001348308.1NP_001335237.1  leucine-rich repeat flightless-interacting protein 2 isoform j

    Status: REVIEWED

    Description
    Transcript Variant: This variant (16) has a longer 5' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (j) is shorter, compared to isoform a. Variants 16 and 17 both encode the same isoform (j).
    Source sequence(s)
    AC006583, AC126118
    Conserved Domains (2) summary
    pfam04111
    Location:339434
    APG6; Autophagy protein Apg6
    pfam09738
    Location:47359
    LRRFIP; LRRFIP family
  15. NM_001348309.1NP_001335238.1  leucine-rich repeat flightless-interacting protein 2 isoform j

    Status: REVIEWED

    Description
    Transcript Variant: This variant (17) has a longer 5' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (j) is shorter, compared to isoform a. Variants 16 and 17 both encode the same isoform (j).
    Source sequence(s)
    AC006583, AC126118
    Conserved Domains (2) summary
    pfam04111
    Location:339434
    APG6; Autophagy protein Apg6
    pfam09738
    Location:47359
    LRRFIP; LRRFIP family
  16. NM_001348310.1NP_001335239.1  leucine-rich repeat flightless-interacting protein 2 isoform k

    Status: REVIEWED

    Description
    Transcript Variant: This variant (18) has a longer 5' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (k) is shorter, compared to isoform a. Variants 3 and 18 both encode the same isoform (k).
    Source sequence(s)
    AC006583, AC126118
    Consensus CDS
    CCDS46791.1
    UniProtKB/Swiss-Prot
    Q9Y608
    Related
    ENSP00000405480.1, ENST00000440230.5
    Conserved Domains (2) summary
    pfam04111
    Location:329424
    APG6; Autophagy protein Apg6
    pfam09738
    Location:47349
    LRRFIP; LRRFIP family
  17. NM_001348311.1NP_001335240.1  leucine-rich repeat flightless-interacting protein 2 isoform l

    Status: REVIEWED

    Description
    Transcript Variant: This variant (19) has a longer 5' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (l) is shorter, compared to isoform a. Variants 2 and 19 both encode the same isoform (l).
    Source sequence(s)
    AC006583, AC126118
    Consensus CDS
    CCDS2665.1
    UniProtKB/Swiss-Prot
    Q9Y608
    Conserved Domains (2) summary
    pfam04111
    Location:305400
    APG6; Autophagy protein Apg6
    pfam09738
    Location:47325
    LRRFIP; LRRFIP family
  18. NM_006309.4NP_006300.1  leucine-rich repeat flightless-interacting protein 2 isoform a

    See identical proteins and their annotated locations for NP_006300.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a, also known as 1).
    Source sequence(s)
    AF115509, AK024692, BC053668, R27776
    Consensus CDS
    CCDS2664.1
    UniProtKB/Swiss-Prot
    Q9Y608
    Related
    ENSP00000338727.4, ENST00000336686.9
    Conserved Domains (2) summary
    pfam09738
    Location:292646
    LRRFIP; LRRFIP family
    pfam11932
    Location:662721
    DUF3450; Protein of unknown function (DUF3450)
  19. NM_017724.2NP_060194.1  leucine-rich repeat flightless-interacting protein 2 isoform l

    See identical proteins and their annotated locations for NP_060194.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) has a longer 5' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (l, also known as 2) is shorter, compared to isoform a.
    Source sequence(s)
    AK024692, BC053668, DC336346, R27776
    Consensus CDS
    CCDS2665.1
    UniProtKB/Swiss-Prot
    Q9Y608
    Related
    ENSP00000346349.4, ENST00000354379.8
    Conserved Domains (2) summary
    pfam04111
    Location:305400
    APG6; Autophagy protein Apg6
    pfam09738
    Location:47325
    LRRFIP; LRRFIP family

RNA

  1. NR_145514.2 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (20) uses an alternate 3' exon structure, compared to variant 1. This variant is represented as non-coding because it lacks the entire coding region found in variant 1.
    Source sequence(s)
    AC126118

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    37052626..37176817 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024453824.1XP_024309592.1  leucine-rich repeat flightless-interacting protein 2 isoform X25

    Conserved Domains (2) summary
    pfam04111
    Location:370465
    APG6; Autophagy protein Apg6
    pfam09738
    Location:47390
    LRRFIP; LRRFIP family
  2. XM_024453821.1XP_024309589.1  leucine-rich repeat flightless-interacting protein 2 isoform X14

    Conserved Domains (3) summary
    pfam04111
    Location:563658
    APG6; Autophagy protein Apg6
    pfam04156
    Location:336459
    IncA; IncA protein
    pfam09738
    Location:229583
    LRRFIP; LRRFIP family
  3. XM_024453820.1XP_024309588.1  leucine-rich repeat flightless-interacting protein 2 isoform X6

    Conserved Domains (3) summary
    pfam04111
    Location:609704
    APG6; Autophagy protein Apg6
    pfam04156
    Location:382505
    IncA; IncA protein
    pfam09738
    Location:275629
    LRRFIP; LRRFIP family
  4. XM_005265539.2XP_005265596.1  leucine-rich repeat flightless-interacting protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005265596.1

    UniProtKB/Swiss-Prot
    Q9Y608
    Conserved Domains (2) summary
    pfam09738
    Location:292646
    LRRFIP; LRRFIP family
    pfam11932
    Location:662721
    DUF3450; Protein of unknown function (DUF3450)
  5. XM_006713400.1XP_006713463.1  leucine-rich repeat flightless-interacting protein 2 isoform X21

    See identical proteins and their annotated locations for XP_006713463.1

    Conserved Domains (2) summary
    PHA02693
    Location:48129
    PHA02693; hypothetical protein; Provisional
    pfam09738
    Location:47429
    DUF2051; Double stranded RNA binding protein (DUF2051)
  6. XM_006713396.1XP_006713459.1  leucine-rich repeat flightless-interacting protein 2 isoform X11

    Conserved Domains (2) summary
    pfam09738
    Location:256610
    DUF2051; Double stranded RNA binding protein (DUF2051)
    pfam13870
    Location:386483
    DUF4201; Domain of unknown function (DUF4201)
  7. XM_024453826.1XP_024309594.1  leucine-rich repeat flightless-interacting protein 2 isoform X27

    Conserved Domains (2) summary
    pfam04111
    Location:339434
    APG6; Autophagy protein Apg6
    pfam09738
    Location:47359
    LRRFIP; LRRFIP family
  8. XM_024453823.1XP_024309591.1  leucine-rich repeat flightless-interacting protein 2 isoform X24

    Conserved Domains (2) summary
    pfam04111
    Location:373468
    APG6; Autophagy protein Apg6
    pfam09738
    Location:47393
    LRRFIP; LRRFIP family
  9. XM_017007473.1XP_016862962.1  leucine-rich repeat flightless-interacting protein 2 isoform X22

  10. XM_017007479.1XP_016862968.1  leucine-rich repeat flightless-interacting protein 2 isoform X26

  11. XM_017007471.1XP_016862960.1  leucine-rich repeat flightless-interacting protein 2 isoform X19

  12. XM_006713394.1XP_006713457.1  leucine-rich repeat flightless-interacting protein 2 isoform X9

    Conserved Domains (2) summary
    pfam09738
    Location:261615
    DUF2051; Double stranded RNA binding protein (DUF2051)
    pfam13870
    Location:391488
    DUF4201; Domain of unknown function (DUF4201)
  13. XM_006713389.1XP_006713452.1  leucine-rich repeat flightless-interacting protein 2 isoform X6

    See identical proteins and their annotated locations for XP_006713452.1

    Conserved Domains (3) summary
    pfam04111
    Location:609704
    APG6; Autophagy protein Apg6
    pfam04156
    Location:382505
    IncA; IncA protein
    pfam09738
    Location:275629
    LRRFIP; LRRFIP family
  14. XM_017007472.1XP_016862961.1  leucine-rich repeat flightless-interacting protein 2 isoform X20

  15. XM_005265551.1XP_005265608.1  leucine-rich repeat flightless-interacting protein 2 isoform X18

    Conserved Domains (1) summary
    pfam09738
    Location:47465
    DUF2051; Double stranded RNA binding protein (DUF2051)
  16. XM_006713386.1XP_006713449.1  leucine-rich repeat flightless-interacting protein 2 isoform X3

    Conserved Domains (2) summary
    pfam09738
    Location:278632
    DUF2051; Double stranded RNA binding protein (DUF2051)
    pfam13870
    Location:408505
    DUF4201; Domain of unknown function (DUF4201)
  17. XM_006713388.1XP_006713451.1  leucine-rich repeat flightless-interacting protein 2 isoform X5

    Conserved Domains (2) summary
    pfam09738
    Location:276630
    DUF2051; Double stranded RNA binding protein (DUF2051)
    pfam13870
    Location:406503
    DUF4201; Domain of unknown function (DUF4201)
  18. XM_006713385.1XP_006713448.1  leucine-rich repeat flightless-interacting protein 2 isoform X2

    Conserved Domains (2) summary
    pfam09738
    Location:291645
    DUF2051; Double stranded RNA binding protein (DUF2051)
    pfam13870
    Location:421518
    DUF4201; Domain of unknown function (DUF4201)
  19. XM_006713387.1XP_006713450.1  leucine-rich repeat flightless-interacting protein 2 isoform X4

    Conserved Domains (1) summary
    pfam09738
    Location:277631
    DUF2051; Double stranded RNA binding protein (DUF2051)
  20. XM_006713397.1XP_006713460.1  leucine-rich repeat flightless-interacting protein 2 isoform X16

    Conserved Domains (1) summary
    pfam09738
    Location:218574
    DUF2051; Double stranded RNA binding protein (DUF2051)
  21. XM_017007466.1XP_016862955.1  leucine-rich repeat flightless-interacting protein 2 isoform X12

  22. XM_006713393.1XP_006713456.1  leucine-rich repeat flightless-interacting protein 2 isoform X8

    Conserved Domains (1) summary
    pfam09738
    Location:262616
    DUF2051; Double stranded RNA binding protein (DUF2051)
  23. XM_017007469.1XP_016862958.1  leucine-rich repeat flightless-interacting protein 2 isoform X17

  24. XM_017007467.1XP_016862956.1  leucine-rich repeat flightless-interacting protein 2 isoform X13

  25. XM_006713392.1XP_006713455.1  leucine-rich repeat flightless-interacting protein 2 isoform X7

    Conserved Domains (2) summary
    pfam09738
    Location:292622
    DUF2051; Double stranded RNA binding protein (DUF2051)
    pfam13870
    Location:398495
    DUF4201; Domain of unknown function (DUF4201)
  26. XM_011534222.1XP_011532524.1  leucine-rich repeat flightless-interacting protein 2 isoform X15

    Conserved Domains (2) summary
    pfam09738
    Location:292581
    DUF2051; Double stranded RNA binding protein (DUF2051)
    pfam17031
    Location:348404
    DUF5101; Domain of unknown function (DUF5101)
  27. XM_006713395.1XP_006713458.1  leucine-rich repeat flightless-interacting protein 2 isoform X10

    Conserved Domains (3) summary
    pfam09738
    Location:292615
    DUF2051; Double stranded RNA binding protein (DUF2051)
    cd16269
    Location:462475
    GBP_C; coiled coil [structural motif]
    cl20817
    Location:342482
    GBP_C; Guanylate-binding protein, C-terminal domain
  28. XM_011534217.1XP_011532519.1  leucine-rich repeat flightless-interacting protein 2 isoform X1

    See identical proteins and their annotated locations for XP_011532519.1

    UniProtKB/Swiss-Prot
    Q9Y608
    Conserved Domains (2) summary
    pfam09738
    Location:292646
    LRRFIP; LRRFIP family
    pfam11932
    Location:662721
    DUF3450; Protein of unknown function (DUF3450)
  29. XM_017007484.1XP_016862973.1  leucine-rich repeat flightless-interacting protein 2 isoform X28

    UniProtKB/Swiss-Prot
    Q9Y608
    Conserved Domains (2) summary
    pfam04111
    Location:329424
    APG6; Autophagy protein Apg6
    pfam09738
    Location:47349
    LRRFIP; LRRFIP family
  30. XM_017007476.1XP_016862965.1  leucine-rich repeat flightless-interacting protein 2 isoform X23

    Conserved Domains (2) summary
    pfam09738
    Location:47414
    LRRFIP; LRRFIP family
    cl25732
    Location:187488
    SMC_N; RecF/RecN/SMC N terminal domain
  31. XM_011534229.1XP_011532531.1  leucine-rich repeat flightless-interacting protein 2 isoform X21

    See identical proteins and their annotated locations for XP_011532531.1

    Conserved Domains (2) summary
    PHA02693
    Location:48129
    PHA02693; hypothetical protein; Provisional
    pfam09738
    Location:47429
    DUF2051; Double stranded RNA binding protein (DUF2051)
  32. XM_006713390.1XP_006713453.1  leucine-rich repeat flightless-interacting protein 2 isoform X6

    See identical proteins and their annotated locations for XP_006713453.1

    Conserved Domains (3) summary
    pfam04111
    Location:609704
    APG6; Autophagy protein Apg6
    pfam04156
    Location:382505
    IncA; IncA protein
    pfam09738
    Location:275629
    LRRFIP; LRRFIP family
  33. XM_011534218.1XP_011532520.1  leucine-rich repeat flightless-interacting protein 2 isoform X1

    See identical proteins and their annotated locations for XP_011532520.1

    UniProtKB/Swiss-Prot
    Q9Y608
    Conserved Domains (2) summary
    pfam09738
    Location:292646
    LRRFIP; LRRFIP family
    pfam11932
    Location:662721
    DUF3450; Protein of unknown function (DUF3450)
  34. XM_011534219.1XP_011532521.1  leucine-rich repeat flightless-interacting protein 2 isoform X1

    See identical proteins and their annotated locations for XP_011532521.1

    UniProtKB/Swiss-Prot
    Q9Y608
    Conserved Domains (2) summary
    pfam09738
    Location:292646
    LRRFIP; LRRFIP family
    pfam11932
    Location:662721
    DUF3450; Protein of unknown function (DUF3450)
  35. XM_005265540.1XP_005265597.1  leucine-rich repeat flightless-interacting protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005265597.1

    UniProtKB/Swiss-Prot
    Q9Y608
    Conserved Domains (2) summary
    pfam09738
    Location:292646
    LRRFIP; LRRFIP family
    pfam11932
    Location:662721
    DUF3450; Protein of unknown function (DUF3450)

RNA

  1. XR_001740363.1 RNA Sequence

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