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ZMYM5 zinc finger MYM-type containing 5 [ Homo sapiens (human) ]

Gene ID: 9205, updated on 21-Dec-2019

Summary

Official Symbol
ZMYM5provided by HGNC
Official Full Name
zinc finger MYM-type containing 5provided by HGNC
Primary source
HGNC:HGNC:13029
See related
Ensembl:ENSG00000132950 MIM:616443
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MYM; ZNF237; HSPC050; ZNF198L1
Expression
Ubiquitous expression in testis (RPKM 10.0), gall bladder (RPKM 4.8) and 25 other tissues See more
Orthologs

Genomic context

See ZMYM5 in Genome Data Viewer
Location:
13q12.11
Exon count:
9
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 13 NC_000013.11 (19823482..19863649, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (20397621..20437776, complement)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene paraspeckle component 1 Neighboring gene RNA, 7SL, cytoplasmic 166, pseudogene Neighboring gene ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 pseudogene 1 Neighboring gene zinc finger MYM-type containing 2 Neighboring gene KRR1 pseudogene 1 Neighboring gene long intergenic non-protein coding RNA 1072

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA-binding transcription factor activity, RNA polymerase II-specific IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of cell morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger MYM-type protein 5
Names
zinc finger protein 198-like 1
zinc finger protein 237
zinc finger, MYM-type 5

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039649.2NP_001034738.1  zinc finger MYM-type protein 5 isoform 2

    See identical proteins and their annotated locations for NP_001034738.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR and has multiple differences in the 3' coding region, compared to variant 3. These differences result in a protein (isoform 2) with a shorter and distinct C-terminus, compared to isoform 3.
    Source sequence(s)
    AJ133353, AL355001, BC007048
    Consensus CDS
    CCDS31943.1
    UniProtKB/Swiss-Prot
    Q9UJ78
    Related
    ENSP00000372364.4, ENST00000382907.8
  2. NM_001039650.2NP_001034739.1  zinc finger MYM-type protein 5 isoform 1

    See identical proteins and their annotated locations for NP_001034739.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) differs in the 3' UTR and has multiple differences in the 3' coding region, compared to variant 3. These differences result in a protein (isoform 1) with a shorter and distinct C-terminus, compared to isoform 3.
    Source sequence(s)
    AJ133352, AL355001, BC007048
    Consensus CDS
    CCDS31942.1
    UniProtKB/Swiss-Prot
    Q9UJ78
    Related
    ENSP00000372361.4, ENST00000382905.8
    Conserved Domains (1) summary
    pfam06467
    Location:241276
    zf-FCS; MYM-type Zinc finger with FCS sequence motif
  3. NM_001142684.2NP_001136156.1  zinc finger MYM-type protein 5 isoform 3

    See identical proteins and their annotated locations for NP_001136156.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3). There are no full-length transcripts representing the exon combination of this variant in human; it is predicted based on partial transcript alignments, on alignment of the macaque mRNA AB179330.1, and on homology support for the encoded protein.
    Source sequence(s)
    AJ133352, AL354808, AL355001, BU853478
    UniProtKB/Swiss-Prot
    Q9UJ78
    Related
    ENSP00000337034.4, ENST00000337963.9
    Conserved Domains (2) summary
    smart00597
    Location:563638
    ZnF_TTF; zinc finger in transposases and transcription factors
    pfam06467
    Location:372415
    zf-FCS; MYM-type Zinc finger with FCS sequence motif

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p13 Primary Assembly

    Range
    19823482..19863649 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024449435.1XP_024305203.1  zinc finger MYM-type protein 5 isoform X5

    Conserved Domains (2) summary
    smart00597
    Location:235310
    ZnF_TTF; zinc finger in transposases and transcription factors
    pfam06467
    Location:4787
    zf-FCS; MYM-type Zinc finger with FCS sequence motif
  2. XM_005266594.3XP_005266651.1  zinc finger MYM-type protein 5 isoform X2

    See identical proteins and their annotated locations for XP_005266651.1

    UniProtKB/Swiss-Prot
    Q9UJ78
    Conserved Domains (2) summary
    smart00597
    Location:563638
    ZnF_TTF; zinc finger in transposases and transcription factors
    pfam06467
    Location:372415
    zf-FCS; MYM-type Zinc finger with FCS sequence motif
  3. XM_024449433.1XP_024305201.1  zinc finger MYM-type protein 5 isoform X4

  4. XM_024449434.1XP_024305202.1  zinc finger MYM-type protein 5 isoform X5

    Conserved Domains (2) summary
    smart00597
    Location:235310
    ZnF_TTF; zinc finger in transposases and transcription factors
    pfam06467
    Location:4787
    zf-FCS; MYM-type Zinc finger with FCS sequence motif
  5. XM_011535310.2XP_011533612.1  zinc finger MYM-type protein 5 isoform X3

    Conserved Domains (2) summary
    smart00597
    Location:408483
    ZnF_TTF; zinc finger in transposases and transcription factors
    pfam06467
    Location:217260
    zf-FCS; MYM-type Zinc finger with FCS sequence motif
  6. XM_011535309.2XP_011533611.1  zinc finger MYM-type protein 5 isoform X1

    Conserved Domains (2) summary
    smart00597
    Location:590665
    ZnF_TTF; zinc finger in transposases and transcription factors
    pfam06467
    Location:399442
    zf-FCS; MYM-type Zinc finger with FCS sequence motif
  7. XM_005266593.4XP_005266650.1  zinc finger MYM-type protein 5 isoform X2

    See identical proteins and their annotated locations for XP_005266650.1

    UniProtKB/Swiss-Prot
    Q9UJ78
    Conserved Domains (2) summary
    smart00597
    Location:563638
    ZnF_TTF; zinc finger in transposases and transcription factors
    pfam06467
    Location:372415
    zf-FCS; MYM-type Zinc finger with FCS sequence motif
  8. XM_006719894.3XP_006719957.1  zinc finger MYM-type protein 5 isoform X2

    See identical proteins and their annotated locations for XP_006719957.1

    UniProtKB/Swiss-Prot
    Q9UJ78
    Conserved Domains (2) summary
    smart00597
    Location:563638
    ZnF_TTF; zinc finger in transposases and transcription factors
    pfam06467
    Location:372415
    zf-FCS; MYM-type Zinc finger with FCS sequence motif
  9. XM_024449438.1XP_024305206.1  zinc finger MYM-type protein 5 isoform X9

  10. XM_024449437.1XP_024305205.1  zinc finger MYM-type protein 5 isoform X8

  11. XM_024449436.1XP_024305204.1  zinc finger MYM-type protein 5 isoform X6

    Conserved Domains (1) summary
    smart00746
    Location:271307
    TRASH; metallochaperone-like domain
  12. XM_017020851.2XP_016876340.1  zinc finger MYM-type protein 5 isoform X7

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_014242.1: Suppressed sequence

    Description
    NM_014242.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
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