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TPGS1 tubulin polyglutamylase complex subunit 1 [ Homo sapiens (human) ]

Gene ID: 91978, updated on 17-Jun-2019

Summary

Official Symbol
TPGS1provided by HGNC
Official Full Name
tubulin polyglutamylase complex subunit 1provided by HGNC
Primary source
HGNC:HGNC:25058
See related
Ensembl:ENSG00000141933
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PGs1; C19orf20; GTRGEO22
Expression
Broad expression in kidney (RPKM 5.9), fat (RPKM 4.3) and 18 other tissues See more
Orthologs

Genomic context

See TPGS1 in Genome Data Viewer
Location:
19p13.3
Exon count:
2
Annotation release Status Assembly Chr Location
109.20190607 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (507497..519654)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (507497..519654)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene outer dense fiber of sperm tails 3 like 2 Neighboring gene uncharacterized LOC105372232 Neighboring gene mucosal vascular addressin cell adhesion molecule 1 Neighboring gene cell division cycle 34 Neighboring gene granzyme M

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
microtubule binding IEA
Inferred from Electronic Annotation
more info
 
tubulin-glutamic acid ligase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
adult behavior IEA
Inferred from Electronic Annotation
more info
 
chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
protein polyglutamylation IEA
Inferred from Electronic Annotation
more info
 
sperm axoneme assembly IEA
Inferred from Electronic Annotation
more info
 
vesicle localization IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
axon IEA
Inferred from Electronic Annotation
more info
 
centrosome IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
dendrite IEA
Inferred from Electronic Annotation
more info
 
microtubule IEA
Inferred from Electronic Annotation
more info
 
motile cilium IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
tubulin polyglutamylase complex subunit 1
Names
gene trap ROSA b-geo 22

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_033513.3NP_277048.2  tubulin polyglutamylase complex subunit 1

    See identical proteins and their annotated locations for NP_277048.2

    Status: VALIDATED

    Source sequence(s)
    BC009520, BM846833
    Consensus CDS
    CCDS42454.1
    UniProtKB/Swiss-Prot
    Q6ZTW0
    Related
    ENSP00000352265.4, ENST00000359315.6
    Conserved Domains (1) summary
    cl02594
    Location:3674
    DD_R_PKA; Dimerization/Docking domain of the Regulatory subunit of cAMP-dependent protein kinase and similar domains

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    507497..519654
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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