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C11orf52 chromosome 11 open reading frame 52 [ Homo sapiens (human) ]

Gene ID: 91894, updated on 3-May-2025
Official Symbol
C11orf52provided by HGNC
Official Full Name
chromosome 11 open reading frame 52provided by HGNC
Primary source
HGNC:HGNC:30531
See related
Ensembl:ENSG00000149300 AllianceGenome:HGNC:30531
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Located in extracellular exosome. [provided by Alliance of Genome Resources, May 2025]
Expression
Broad expression in kidney (RPKM 18.9), thyroid (RPKM 11.7) and 16 other tissues See more
Orthologs
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See C11orf52 in Genome Data Viewer
Location:
11q23.1
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (111918913..111926871)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (111929157..111937115)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (111789637..111797595)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene ribosomal protein L37a pseudogene 8 Neighboring gene HSPB2-C11orf52 readthrough (NMD candidate) Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:111784209-111784862 Neighboring gene Sharpr-MPRA regulatory region 8432 Neighboring gene crystallin alpha B Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3903 Neighboring gene heat shock protein family B (small) member 2 Neighboring gene RNA, 5S ribosomal pseudogene 351 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3904 Neighboring gene DIX domain containing 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5523 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3905 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:111848219-111848850 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5524 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5525 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5526 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5527 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5528 Neighboring gene peptidylprolyl isomerase H pseudogene 1 Neighboring gene dihydrolipoamide S-acetyltransferase

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018
Products Interactant Other Gene Complex Source Pubs Description

Readthrough HSPB2-C11orf52

Readthrough gene: HSPB2-C11orf52, Included gene: HSPB2

Clone Names

  • FLJ25219, MGC14839, MGC131888

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular exosome HDA PubMed 
Preferred Names
uncharacterized protein C11orf52

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_080659.3NP_542390.2  uncharacterized protein C11orf52

    See identical proteins and their annotated locations for NP_542390.2

    Status: VALIDATED

    Source sequence(s)
    BC008501, BQ102454
    Consensus CDS
    CCDS8353.1
    UniProtKB/Swiss-Prot
    Q96A22
    Related
    ENSP00000278601.5, ENST00000278601.6
    Conserved Domains (1) summary
    pfam15147
    Location:1123
    DUF4578; Domain of unknown function (DUF4578)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    111918913..111926871
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    111929157..111937115
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)