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TTC5 tetratricopeptide repeat domain 5 [ Homo sapiens (human) ]

Gene ID: 91875, updated on 24-Nov-2020

Summary

Official Symbol
TTC5provided by HGNC
Official Full Name
tetratricopeptide repeat domain 5provided by HGNC
Primary source
HGNC:HGNC:19274
See related
Ensembl:ENSG00000136319 MIM:619014
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Strap
Expression
Ubiquitous expression in testis (RPKM 7.6), thyroid (RPKM 6.4) and 25 other tissues See more
Orthologs

Genomic context

See TTC5 in Genome Data Viewer
Location:
14q11.2
Exon count:
10
Annotation release Status Assembly Chr Location
109.20201120 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (20286227..20305951, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (20757290..20774153, complement)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 11 subfamily H member 7 (gene/pseudogene) Neighboring gene olfactory receptor family 11 subfamily H member 4 Neighboring gene cyclin B1 interacting protein 1 Neighboring gene small nucleolar RNA, H/ACA box 79B Neighboring gene small nucleolar RNA, C/D box 126

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
chromatin binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
DNA repair IEA
Inferred from Electronic Annotation
more info
 
positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
regulation of signal transduction by p53 class mediator TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleoplasm TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
tetratricopeptide repeat protein 5
Names
TPR repeat protein 5
stress-responsive activator of p300

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138376.3NP_612385.2  tetratricopeptide repeat protein 5

    See identical proteins and their annotated locations for NP_612385.2

    Status: VALIDATED

    Source sequence(s)
    AL356019, BC030822, BM998414, BX248066, DB051711
    Consensus CDS
    CCDS9546.1
    UniProtKB/Swiss-Prot
    Q8N0Z6
    UniProtKB/TrEMBL
    Q86T04
    Related
    ENSP00000258821.3, ENST00000258821.8
    Conserved Domains (3) summary
    sd00006
    Location:6897
    TPR; TPR repeat [structural motif]
    pfam13414
    Location:67130
    TPR_11; TPR repeat
    pfam16669
    Location:318429
    TTC5_OB; Tetratricopeptide repeat protein 5 OB fold domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20201120

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    20286227..20305951 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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