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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001396000.1 → NP_001382929.1 rho guanine nucleotide exchange factor 1 isoform 4
Status: REVIEWED
- Source sequence(s)
-
AC243967
- UniProtKB/TrEMBL
-
M0QZR4
- Related
- ENSP00000470715.1, ENST00000599846.5
- Conserved Domains (4) summary
-
- PHA03381
Location:289 → 431
- PHA03381; tegument protein VP22; Provisional
- cd08755
Location:52 → 244
- RGS_p115RhoGEF; Regulator of G protein signaling (RGS) domain found in the Rho guanine nucleotide exchange factor (GEF), p115 RhoGEF
- smart00325
Location:476 → 660
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
- cd14679
Location:694 → 818
- PH_p115RhoGEF; Rho guanine nucleotide exchange factor Pleckstrin homology domain
-
NM_001396002.1 → NP_001382931.1 rho guanine nucleotide exchange factor 1 isoform 5
Status: REVIEWED
- Source sequence(s)
-
AC010616, AC243967
- Conserved Domains (4) summary
-
- smart00325
Location:387 → 571
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
- PHA03169
Location:218 → 382
- PHA03169; hypothetical protein; Provisional
- cd14679
Location:605 → 729
- PH_p115RhoGEF; Rho guanine nucleotide exchange factor Pleckstrin homology domain
- cl02565
Location:52 → 211
- RGS; Regulator of G protein signaling (RGS) domain superfamily
-
NM_001396003.1 → NP_001382932.1 rho guanine nucleotide exchange factor 1 isoform 6
Status: REVIEWED
- Source sequence(s)
-
AC010616, AC243967
- Related
- ENSP00000514042.1, ENST00000698932.1
- Conserved Domains (4) summary
-
- cd08755
Location:52 → 244
- RGS_p115RhoGEF; Regulator of G protein signaling (RGS) domain found in the Rho guanine nucleotide exchange factor (GEF), p115 RhoGEF
- smart00325
Location:420 → 604
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
- PHA03169
Location:251 → 415
- PHA03169; hypothetical protein; Provisional
- cd14679
Location:638 → 762
- PH_p115RhoGEF; Rho guanine nucleotide exchange factor Pleckstrin homology domain
-
NM_001396004.1 → NP_001382933.1 rho guanine nucleotide exchange factor 1 isoform 7
Status: REVIEWED
- Source sequence(s)
-
AC243967
- Related
- ENSP00000367394.3, ENST00000378152.8
- Conserved Domains (4) summary
-
- smart00325
Location:387 → 571
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
- PHA03169
Location:218 → 382
- PHA03169; hypothetical protein; Provisional
- cd14679
Location:605 → 729
- PH_p115RhoGEF; Rho guanine nucleotide exchange factor Pleckstrin homology domain
- cl02565
Location:52 → 211
- RGS; Regulator of G protein signaling (RGS) domain superfamily
-
NM_001396006.1 → NP_001382935.1 rho guanine nucleotide exchange factor 1 isoform 8
Status: REVIEWED
- Source sequence(s)
-
AC243967
- Conserved Domains (4) summary
-
- cd08755
Location:52 → 244
- RGS_p115RhoGEF; Regulator of G protein signaling (RGS) domain found in the Rho guanine nucleotide exchange factor (GEF), p115 RhoGEF
- smart00325
Location:420 → 604
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
- PHA03169
Location:251 → 415
- PHA03169; hypothetical protein; Provisional
- cd14679
Location:638 → 762
- PH_p115RhoGEF; Rho guanine nucleotide exchange factor Pleckstrin homology domain
-
NM_004706.4 → NP_004697.2 rho guanine nucleotide exchange factor 1 isoform 2
See identical proteins and their annotated locations for NP_004697.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) has an alternate 5' exon and uses a downstream start codon, as compared to variant 1. The encoded isoform 2 thus has a shorter N-terminus, as compared to isoform 1.
- Source sequence(s)
-
AC243967, BC005155, BC011726, BM147791
- Consensus CDS
-
CCDS12591.1
- UniProtKB/Swiss-Prot
- Q92888, Q9BSB1
- UniProtKB/TrEMBL
-
A0A024R0R1
- Related
- ENSP00000346532.3, ENST00000354532.8
- Conserved Domains (4) summary
-
- pfam05887
Location:315 → 410
- Trypan_PARP; Procyclic acidic repetitive protein (PARP)
- cd08755
Location:52 → 244
- RGS_p115RhoGEF; Regulator of G protein signaling (RGS) domain found in the Rho guanine nucleotide exchange factor (GEF), p115 RhoGEF
- smart00325
Location:420 → 604
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
- cd14679
Location:638 → 762
- PH_p115RhoGEF; Rho guanine nucleotide exchange factor Pleckstrin homology domain
-
NM_198977.2 → NP_945328.1 rho guanine nucleotide exchange factor 1 isoform 3
See identical proteins and their annotated locations for NP_945328.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) has an alternate 5' exon and lacks an in-frame internal exon, as compared to variant 1. The encoded isoform 3 thus has a shorter N-terminus and lacks an internal segment, as compared to isoform 1.
- Source sequence(s)
-
AC243967, BC011726, BM147791
- Consensus CDS
-
CCDS12592.1
- UniProtKB/Swiss-Prot
-
Q92888
- Related
- ENSP00000344429.3, ENST00000347545.8
- Conserved Domains (4) summary
-
- pfam05887
Location:282 → 377
- Trypan_PARP; Procyclic acidic repetitive protein (PARP)
- smart00325
Location:387 → 571
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
- cd14679
Location:605 → 729
- PH_p115RhoGEF; Rho guanine nucleotide exchange factor Pleckstrin homology domain
- cl02565
Location:52 → 211
- RGS; Regulator of G protein signaling (RGS) domain superfamily
-
NM_199002.2 → NP_945353.1 rho guanine nucleotide exchange factor 1 isoform 1
See identical proteins and their annotated locations for NP_945353.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1).
- Source sequence(s)
-
BC011726, BC034013, BQ944132
- Consensus CDS
-
CCDS12590.1
- UniProtKB/Swiss-Prot
-
Q92888
- Related
- ENSP00000337261.3, ENST00000337665.8
- Conserved Domains (4) summary
-
- pfam05887
Location:330 → 425
- Trypan_PARP; Procyclic acidic repetitive protein (PARP)
- cd08755
Location:67 → 259
- RGS_p115RhoGEF; Regulator of G protein signaling (RGS) domain found in the Rho guanine nucleotide exchange factor (GEF), p115 RhoGEF
- smart00325
Location:435 → 619
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
- cd14679
Location:653 → 777
- PH_p115RhoGEF; Rho guanine nucleotide exchange factor Pleckstrin homology domain
RNA
-
NR_135626.2 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC010616
-
NR_173092.1 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC010616, AC243967
-
NR_173093.1 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC243967
- Related
-
ENST00000698933.1
-
NR_173095.1 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC010616
-
NR_173096.1 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC010616
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000019.10 Reference GRCh38.p14 Primary Assembly
- Range
-
41883184..41930141
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047439662.1 → XP_047295618.1 rho guanine nucleotide exchange factor 1 isoform X1
-
XM_047439664.1 → XP_047295620.1 rho guanine nucleotide exchange factor 1 isoform X3
-
XM_047439665.1 → XP_047295621.1 rho guanine nucleotide exchange factor 1 isoform X4
-
XM_047439663.1 → XP_047295619.1 rho guanine nucleotide exchange factor 1 isoform X2
-
XM_047439666.1 → XP_047295622.1 rho guanine nucleotide exchange factor 1 isoform X5
Alternate T2T-CHM13v2.0
Genomic
-
NC_060943.1 Alternate T2T-CHM13v2.0
- Range
-
44702671..44749424
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)