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LRP5L LDL receptor related protein 5 like [ Homo sapiens (human) ]

Gene ID: 91355, updated on 5-Jan-2022

Summary

Official Symbol
LRP5Lprovided by HGNC
Official Full Name
LDL receptor related protein 5 likeprovided by HGNC
Primary source
HGNC:HGNC:25323
Gene type
pseudo
RefSeq status
MODEL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable coreceptor activity. Predicted to be involved in several processes, including animal organ development; cholesterol homeostasis; and osteoblast development. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Ubiquitous expression in bone marrow (RPKM 1.5), thyroid (RPKM 1.2) and 25 other tissues See more
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Genomic context

See LRP5L in Genome Data Viewer
Location:
22q11.23
Exon count:
8
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 22 NC_000022.11 (25351418..25405410, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene immunoglobulin lambda like polypeptide 3, pseudogene Neighboring gene PHD finger protein 10 pseudogene Neighboring gene conserved acetylation island sequence 2 enhancer Neighboring gene crystallin beta B2 pseudogene 1 Neighboring gene microRNA 6817

Genomic regions, transcripts, and products

Genomic Sequence:
NC_000022.11 Chromosome 22 Reference GRCh38.p13 Primary Assembly

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Other Names

  • LRP-5-like
  • low density lipoprotein receptor-related protein 5-like
  • low-density lipoprotein receptor-related protein 5-like protein

Clone Names

  • DKFZp434O0213

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables coreceptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in adipose tissue development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in anterior/posterior pattern specification IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in bone marrow development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in bone morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in bone remodeling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in branching involved in mammary gland duct morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cholesterol homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in gastrulation with mouth forming second IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in osteoblast development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of insulin secretion involved in cellular response to glucose stimulus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in retinal blood vessel morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p13 Primary Assembly

    Range
    25351418..25405410 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_005228024.1 RNA Sequence

  2. XR_005228025.1 RNA Sequence

  3. XR_005228030.1 RNA Sequence

  4. XR_005228029.1 RNA Sequence

  5. XR_005228027.1 RNA Sequence

  6. XR_005228028.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001135772.2: Suppressed sequence

    Description
    NM_001135772.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.
  2. NM_182492.3: Suppressed sequence

    Description
    NM_182492.3: This RefSeq was removed because it is now thought that this gene is a pseudogene.
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