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LRP5L LDL receptor related protein 5 like (pseudogene) [ Homo sapiens (human) ]

Gene ID: 91355, updated on 25-Oct-2022

Summary

Official Symbol
LRP5Lprovided by HGNC
Official Full Name
LDL receptor related protein 5 like (pseudogene)provided by HGNC
Primary source
HGNC:HGNC:25323
See related
Ensembl:ENSG00000290796 AllianceGenome:HGNC:25323
Gene type
pseudo
RefSeq status
MODEL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable coreceptor activity. Predicted to be involved in several processes, including animal organ development; cholesterol homeostasis; and osteoblast development. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bone marrow (RPKM 1.5), thyroid (RPKM 1.2) and 25 other tissues See more
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Genomic context

See LRP5L in Genome Data Viewer
Location:
22q11.23
Exon count:
8
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (25351418..25405408, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (25812606..25837158, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene immunoglobulin lambda like polypeptide 3, pseudogene Neighboring gene PHD finger protein 10 pseudogene Neighboring gene uncharacterized LOC124905095 Neighboring gene uncharacterized LOC124905093

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Other Names

  • LRP-5-like
  • low density lipoprotein receptor-related protein 5-like
  • low-density lipoprotein receptor-related protein 5-like protein

Clone Names

  • DKFZp434O0213

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables coreceptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in adipose tissue development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in anterior/posterior pattern specification IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in bone marrow development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in bone morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in bone remodeling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in branching involved in mammary gland duct morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cholesterol homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in gastrulation with mouth forming second IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in osteoblast development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of insulin secretion involved in cellular response to glucose stimulus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in retinal blood vessel morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    25351418..25405408 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_005228030.2 RNA Sequence

    Related
    ENST00000444995.7
  2. XR_007068026.1 RNA Sequence

  3. XR_007068032.1 RNA Sequence

  4. XR_007068027.1 RNA Sequence

  5. XR_007068028.1 RNA Sequence

  6. XR_005228024.2 RNA Sequence

  7. XR_007068030.1 RNA Sequence

  8. XR_007068029.1 RNA Sequence

  9. XR_007068031.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    25812606..25837158 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_007090517.1 RNA Sequence

  2. XR_007090516.1 RNA Sequence

  3. XR_007090515.1 RNA Sequence

  4. XR_007090519.1 RNA Sequence

  5. XR_007090521.1 RNA Sequence

  6. XR_007090518.1 RNA Sequence

  7. XR_007090520.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001135772.2: Suppressed sequence

    Description
    NM_001135772.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.
  2. NM_182492.3: Suppressed sequence

    Description
    NM_182492.3: This RefSeq was removed because it is now thought that this gene is a pseudogene.