U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

GUSBP11 GUSB pseudogene 11 [ Homo sapiens (human) ]

Gene ID: 91316, updated on 5-Jul-2025
Official Symbol
GUSBP11provided by HGNC
Official Full Name
GUSB pseudogene 11provided by HGNC
Primary source
HGNC:HGNC:42325
See related
Ensembl:ENSG00000228315 AllianceGenome:HGNC:42325
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This transcribed pseudogene is similar to two functional genes. The 5' portion of the pseudogene is related to glucuronidase, beta, and the 3' portion is related to immunoglobulin lambda-like polypeptide 1. [provided by RefSeq, Jul 2011]
Expression
Ubiquitous expression in bone marrow (RPKM 14.2), spleen (RPKM 9.8) and 25 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table
See GUSBP11 in Genome Data Viewer
Location:
22q11.23
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (23638487..23717423, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (24085633..24164623, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (23980674..24059610, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene aspartate rich 1 Neighboring gene uncharacterized LOC124905089 Neighboring gene ReSE screen-validated silencer GRCh37_chr22:23975547-23975684 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:23991555-23992054 Neighboring gene argininosuccinate lyase pseudogene 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:24016106-24016710 Neighboring gene Sharpr-MPRA regulatory region 3793 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:24037607-24038107 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18756 Neighboring gene ral guanine nucleotide dissociation stimulator like 4 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:24059101-24059740 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:24059741-24060380 Neighboring gene uncharacterized LOC124905088 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:24087516-24088016 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:24088017-24088517 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:24093057-24093732 Neighboring gene zinc finger protein 70

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Related articles in PubMed

  1. Long Noncoding RNA GUSBP11 Knockdown Alleviates Nasopharyngeal Carcinoma via Regulating miR-1226-3p/TM9SF4 Axis. Zhang X, et al. Cancer Biother Radiopharm, 2024 Mar. PMID 35675666
  2. Composite exon structure of an unusual Ig lambda-like gene located at human 22q11 position. Schiff C, et al. Mamm Genome, 1996 Aug. PMID 8678981
  3. Isolation of early immunoglobulin lambda-like gene transcripts in human fetal liver. Schiff C, et al. Eur J Immunol, 1989 Oct. PMID 2511029
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Review eQTL and phenotype association data in this region using PheGenI

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Markers

Other Names

  • glucuronidase, beta pseudogene 11
  • glucuronidase, beta/immunoglobulin lambda-like polypeptide 1 pseudogene

Clone Names

  • FLJ52668

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_024448.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AK056875, AK300413, BC050388, BX538181, DC322250, X52204
    Related
    ENST00000445682.2

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    23638487..23717423 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    24085633..24164623 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials