Format

Send to:

Choose Destination

BOD1 biorientation of chromosomes in cell division 1 [ Homo sapiens (human) ]

Gene ID: 91272, updated on 15-Jun-2019

Summary

Official Symbol
BOD1provided by HGNC
Official Full Name
biorientation of chromosomes in cell division 1provided by HGNC
Primary source
HGNC:HGNC:25114
See related
Ensembl:ENSG00000145919 MIM:616745
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM44B
Expression
Ubiquitous expression in thyroid (RPKM 15.5), ovary (RPKM 14.9) and 25 other tissues See more
Orthologs

Genomic context

See BOD1 in Genome Data Viewer
Location:
5q35.2
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 5 NC_000005.10 (173607145..173617072, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (173034148..173043706, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105377733 Neighboring gene uncharacterized LOC105377735 Neighboring gene uncharacterized LOC285593 Neighboring gene long intergenic non-protein coding RNA 1863 Neighboring gene long intergenic non-protein coding RNA 1942

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
NHGRI GWA Catalog
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
NHGRI GWA Catalog
Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein phosphatase 2A binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein phosphatase 2A binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein phosphatase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein phosphatase inhibitor activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
cell division IEA
Inferred from Electronic Annotation
more info
 
mitotic metaphase plate congression IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitotic sister chromatid biorientation IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitotic sister chromatid cohesion, centromeric IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of phosphoprotein phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of phosphoprotein phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
protein localization to chromosome, centromeric region IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
centrosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
centrosome IDA
Inferred from Direct Assay
more info
PubMed 
condensed chromosome outer kinetochore IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
condensed chromosome outer kinetochore IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
spindle microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
spindle microtubule IDA
Inferred from Direct Assay
more info
PubMed 
spindle pole IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
spindle pole IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
biorientation of chromosomes in cell division protein 1
Names
biorientation defective 1
family with sequence similarity 44, member B

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159651.1NP_001153123.1  biorientation of chromosomes in cell division protein 1 isoform b

    See identical proteins and their annotated locations for NP_001153123.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon in the 3' coding region, compared to variant 1, that causes a frameshift. The resulting protein (isoform b) has a distinct and shorter C-terminus, compared to isoform a.
    Source sequence(s)
    BC003114, BQ881883, DA506589, DA953541
    Consensus CDS
    CCDS54951.1
    UniProtKB/Swiss-Prot
    Q96IK1
    Related
    ENSP00000285908.5, ENST00000285908.5
    Conserved Domains (1) summary
    pfam05205
    Location:55121
    COMPASS-Shg1; COMPASS (Complex proteins associated with Set1p) component shg1
  2. NM_138369.3NP_612378.1  biorientation of chromosomes in cell division protein 1 isoform a

    See identical proteins and their annotated locations for NP_612378.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    BC007436, BQ881883, DA506589
    Consensus CDS
    CCDS4389.1
    UniProtKB/Swiss-Prot
    Q96IK1
    Related
    ENSP00000309644.4, ENST00000311086.8
    Conserved Domains (1) summary
    pfam05205
    Location:55148
    COMPASS-Shg1; COMPASS (Complex proteins associated with Set1p) component shg1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    173607145..173617072 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017010017.2XP_016865506.1  biorientation of chromosomes in cell division protein 1 isoform X1

RNA

  1. XR_001742334.2 RNA Sequence

  2. XR_941120.3 RNA Sequence

Support Center