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TIGD7 tigger transposable element derived 7 [ Homo sapiens (human) ]

Gene ID: 91151, updated on 12-Oct-2019

Summary

Official Symbol
TIGD7provided by HGNC
Official Full Name
tigger transposable element derived 7provided by HGNC
Primary source
HGNC:HGNC:18331
See related
Ensembl:ENSG00000140993 MIM:612969
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Sancho
Summary
The protein encoded by this gene belongs to the tigger subfamily of the pogo superfamily of DNA-mediated transposons in humans. These proteins are related to DNA transposons found in fungi and nematodes, and more distantly to the Tc1 and mariner transposases. They are also very similar to the major mammalian centromere protein B. The exact function of this gene is not known. [provided by RefSeq, Jul 2008]
Expression
Broad expression in testis (RPKM 5.6), ovary (RPKM 4.8) and 25 other tissues See more
Orthologs

Genomic context

See TIGD7 in Genome Data Viewer
Location:
16p13.3
Exon count:
2
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (3298808..3305430, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (3348808..3355439, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene MEFV innate immuity regulator, pyrin Neighboring gene long intergenic non-protein coding RNA 921 Neighboring gene zinc finger protein 263 Neighboring gene zinc finger protein 75a Neighboring gene ribosomal protein L7 like 1 pseudogene Neighboring gene olfactory receptor family 2 subfamily C member 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ98002, FLJ99447

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
tigger transposable element-derived protein 7

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_033208.4NP_149985.2  tigger transposable element-derived protein 7

    See identical proteins and their annotated locations for NP_149985.2

    Status: REVIEWED

    Source sequence(s)
    AC004232, AI925903, AK308054, BX463753, DC351858
    Consensus CDS
    CCDS10500.1
    UniProtKB/Swiss-Prot
    Q6NT04
    Related
    ENSP00000380071.1, ENST00000396862.2
    Conserved Domains (3) summary
    pfam03221
    Location:77135
    HTH_Tnp_Tc5; Tc5 transposase DNA-binding domain
    cl21459
    Location:455
    HTH; Helix-turn-helix domains
    cl21549
    Location:207399
    rve; Integrase core domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    3298808..3305430 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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