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TRIM47 tripartite motif containing 47 [ Homo sapiens (human) ]

Gene ID: 91107, updated on 7-Jun-2020

Summary

Official Symbol
TRIM47provided by HGNC
Official Full Name
tripartite motif containing 47provided by HGNC
Primary source
HGNC:HGNC:19020
See related
Ensembl:ENSG00000132481 MIM:611041
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GOA; RNF100
Expression
Ubiquitous expression in brain (RPKM 11.4), kidney (RPKM 8.9) and 24 other tissues See more
Orthologs

Genomic context

See TRIM47 in Genome Data Viewer
Location:
17q25.1
Exon count:
7
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (75874164..75878599, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (73870242..73874683, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 1193 Neighboring gene unc-13 homolog D Neighboring gene WW domain binding protein 2 Neighboring gene tripartite motif containing 65 Neighboring gene mitochondrial ribosomal protein L38

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ubiquitin-protein transferase activity IDA
Inferred from Direct Assay
more info
PubMed 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
protein ubiquitination IDA
Inferred from Direct Assay
more info
PubMed 
protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
E3 ubiquitin-protein ligase TRIM47
Names
RING finger protein 100
gene overexpressed in astrocytoma protein
tripartite motif-containing protein 47
NP_258411.2
XP_005257844.1
XP_005257845.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_033452.3NP_258411.2  E3 ubiquitin-protein ligase TRIM47

    See identical proteins and their annotated locations for NP_258411.2

    Status: VALIDATED

    Source sequence(s)
    AC087289, AY026763, BG385464
    Consensus CDS
    CCDS32737.1
    UniProtKB/Swiss-Prot
    Q96LD4
    Related
    ENSP00000254816.1, ENST00000254816.6
    Conserved Domains (3) summary
    pfam00643
    Location:178217
    zf-B_box; B-box zinc finger
    cd15808
    Location:421626
    SPRY_PRY_TRIM47; PRY/SPRY domain in tripartite motif-containing protein 47 (TRIM47), also known as RING finger protein 100 (RNF100) or Gene overexpressed in astrocytoma protein (GOA)
    cl17238
    Location:957
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    75874164..75878599 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005257787.4XP_005257844.1  E3 ubiquitin-protein ligase TRIM47 isoform X1

    See identical proteins and their annotated locations for XP_005257844.1

    UniProtKB/Swiss-Prot
    Q96LD4
    Conserved Domains (1) summary
    cd15808
    Location:183388
    SPRY_PRY_TRIM47; PRY/SPRY domain in tripartite motif-containing protein 47 (TRIM47), also known as RING finger protein 100 (RNF100) or Gene overexpressed in astrocytoma protein (GOA)
  2. XM_005257788.5XP_005257845.1  E3 ubiquitin-protein ligase TRIM47 isoform X1

    See identical proteins and their annotated locations for XP_005257845.1

    UniProtKB/Swiss-Prot
    Q96LD4
    Conserved Domains (1) summary
    cd15808
    Location:183388
    SPRY_PRY_TRIM47; PRY/SPRY domain in tripartite motif-containing protein 47 (TRIM47), also known as RING finger protein 100 (RNF100) or Gene overexpressed in astrocytoma protein (GOA)
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