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groEL molecular chaperone GroEL [ Mycobacterium leprae TN ]

Gene ID: 908906, updated on 26-Dec-2017

Summary

Gene symbol
groEL
Gene description
molecular chaperone GroEL
Locus tag
ML0317
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium leprae TN (strain: TN)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium

Genomic context

Sequence:
NC_002677.1 (405518..407143)

NC_002677.1Genomic Context describing neighboring genes Neighboring gene short chain dehydrogenase Neighboring gene TetR/AcrR family transcriptional regulator Neighboring gene pseudo Neighboring gene lipoprotein

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

  • RNA degradation, organism-specific biosystem (from KEGG)
    RNA degradation, organism-specific biosystemThe correct processing, quality control and turnover of cellular RNA molecules are critical to many aspects in the expression of genetic information. In eukaryotes, two major pathways of mRNA decay e...
  • RNA degradation, conserved biosystem (from KEGG)
    RNA degradation, conserved biosystemThe correct processing, quality control and turnover of cellular RNA molecules are critical to many aspects in the expression of genetic information. In eukaryotes, two major pathways of mRNA decay e...
  • Tuberculosis, organism-specific biosystem (from KEGG)
    Tuberculosis, organism-specific biosystemTuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent...
  • Tuberculosis, conserved biosystem (from KEGG)
    Tuberculosis, conserved biosystemTuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent...

General protein information

Names
molecular chaperone GroEL
NP_301345.1
  • '60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth'

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002677.1 Reference assembly

    Range
    405518..407143
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_301345.1 molecular chaperone GroEL [Mycobacterium leprae TN]

    See identical proteins and their annotated locations for NP_301345.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P09239
    Conserved Domains (1) summary
    PRK00013
    Location:1539
    groEL; chaperonin GroEL; Reviewed
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