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PPP1R3E protein phosphatase 1 regulatory subunit 3E [ Homo sapiens (human) ]

Gene ID: 90673, updated on 23-Nov-2021

Summary

Official Symbol
PPP1R3Eprovided by HGNC
Official Full Name
protein phosphatase 1 regulatory subunit 3Eprovided by HGNC
Primary source
HGNC:HGNC:14943
See related
Ensembl:ENSG00000235194 MIM:619540
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in thyroid (RPKM 5.2), testis (RPKM 5.2) and 25 other tissues See more
Orthologs
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Genomic context

See PPP1R3E in Genome Data Viewer
Location:
14q11.2
Exon count:
5
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (23295652..23302859, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (23764861..23772068, complement)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene ring finger protein 212B Neighboring gene high mobility group nucleosomal binding domain 2 pseudogene 1 Neighboring gene homeobox and leucine zipper encoding Neighboring gene BCL2L2-PABPN1 readthrough Neighboring gene H3 histone pseudogene 37 Neighboring gene BCL2 like 2 Neighboring gene poly(A) binding protein nuclear 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: HOMEZ

Homology

Clone Names

  • KIAA1443

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables [phosphorylase] phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables glycogen binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein phosphatase 1 binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in glycogen metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of glycogen biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of glycogen biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in glycogen granule ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
part_of protein phosphatase type 1 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
protein phosphatase 1 regulatory subunit 3E
Names
protein phosphatase 1, regulatory (inhibitor) subunit 3E

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001276318.2NP_001263247.1  protein phosphatase 1 regulatory subunit 3E

    See identical proteins and their annotated locations for NP_001263247.1

    Status: VALIDATED

    Source sequence(s)
    AK024489, AL049829
    Consensus CDS
    CCDS61403.1
    UniProtKB/Swiss-Prot
    Q9H7J1
    Related
    ENSP00000408288.3, ENST00000452015.9
    Conserved Domains (1) summary
    pfam03370
    Location:156258
    CBM_21; Carbohydrate/starch-binding module (family 21)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    23295652..23302859 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_026862.1: Suppressed sequence

    Description
    NR_026862.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
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