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CARMIL3 capping protein regulator and myosin 1 linker 3 [ Homo sapiens (human) ]

Gene ID: 90668, updated on 23-Nov-2021

Summary

Official Symbol
CARMIL3provided by HGNC
Official Full Name
capping protein regulator and myosin 1 linker 3provided by HGNC
Primary source
HGNC:HGNC:20272
See related
Ensembl:ENSG00000186648 MIM:614716
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
crml-1; LRRC16B; C14orf121
Expression
Broad expression in skin (RPKM 2.9), brain (RPKM 2.8) and 19 other tissues See more
Orthologs
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Genomic context

See CARMIL3 in Genome Data Viewer
Location:
14q11.2
Exon count:
40
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (24052009..24069729)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (24521218..24538938)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene dehydrogenase/reductase 4 like 2 Neighboring gene dehydrogenase/reductase 4 like 1 Neighboring gene uncharacterized LOC105370412 Neighboring gene copine 6 Neighboring gene neural retina leucine zipper Neighboring gene phosphoenolpyruvate carboxykinase 2, mitochondrial

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
capping protein, Arp2/3 and myosin-I linker protein 3
Names
capping protein regulator and myosin 1 linker protein 3
leucine rich repeat containing 16B
leucine-rich repeat-containing protein 16B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138360.4NP_612369.3  capping protein, Arp2/3 and myosin-I linker protein 3

    See identical proteins and their annotated locations for NP_612369.3

    Status: VALIDATED

    Source sequence(s)
    AI017934, AK074167, AL136295, AL834197, BC008134, BG913168, BU102125, DA121863, DT932621
    Consensus CDS
    CCDS32054.1
    UniProtKB/Swiss-Prot
    Q8ND23
    Related
    ENSP00000340467.5, ENST00000342740.6
    Conserved Domains (4) summary
    cd00116
    Location:339600
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:275303
    LRR_RI; leucine-rich repeat [structural motif]
    sd00034
    Location:245273
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam16000
    Location:7781063
    CARMIL_C; CARMIL C-terminus

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    24052009..24069729
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 PATCHES

Genomic

  1. NW_018654722.1 Reference GRCh38.p13 PATCHES

    Range
    352987..370707
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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