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TGIF2LY TGFB induced factor homeobox 2 like Y-linked [ Homo sapiens (human) ]

Gene ID: 90655, updated on 11-Jun-2021

Summary

Official Symbol
TGIF2LYprovided by HGNC
Official Full Name
TGFB induced factor homeobox 2 like Y-linkedprovided by HGNC
Primary source
HGNC:HGNC:18569
See related
Ensembl:ENSG00000176679 MIM:400025
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TGIFLY
Summary
This gene encodes a member of the TALE/TGIF homeobox family of transcription factors. This gene lies within the male specific region of chromosome Y, in a block of sequence that is thought to be the result of a large X-to-Y transposition. The C-terminus of this protein is divergent from that of its chromosome X homolog (TGIF2LX), suggesting that this protein may act as a regulator of TGIF2LX. [provided by RefSeq, Jul 2008]
Expression
Restricted expression toward testis (RPKM 4.4) See more
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Genomic context

See TGIF2LY in Genome Data Viewer
Location:
Yp11.2
Exon count:
2
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) Y NC_000024.10 (3579067..3580041)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) Y NC_000024.9 (3447108..3448082)

Chromosome Y - NC_000024.10Genomic Context describing neighboring genes Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 5 pseudogene 1 Neighboring gene proline rich coiled-coil 2C pseudogene 1 Neighboring gene USP12 pseudogene Y-linked Neighboring gene ring finger protein 19B pseudogene Y-linked

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
homeobox protein TGIF2LY
Names
TGF-beta-induced transcription factor 2-like protein
TGFB-induced factor 2-like protein, Y-linked
TGFB-induced factor 2-like, Y-linked
TGIF-like on the Y

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_139214.3NP_631960.1  homeobox protein TGIF2LY

    See identical proteins and their annotated locations for NP_631960.1

    Status: REVIEWED

    Source sequence(s)
    AC019058, AF332223
    Consensus CDS
    CCDS14775.1
    UniProtKB/Swiss-Prot
    Q8IUE0
    Related
    ENSP00000318502.4, ENST00000321217.5
    Conserved Domains (1) summary
    pfam05920
    Location:68107
    Homeobox_KN; Homeobox KN domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000024.10 Reference GRCh38.p13 Primary Assembly

    Range
    3579067..3580041
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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