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GADD45GIP1 GADD45G interacting protein 1 [ Homo sapiens (human) ]

Gene ID: 90480, updated on 5-Apr-2020

Summary

Official Symbol
GADD45GIP1provided by HGNC
Official Full Name
GADD45G interacting protein 1provided by HGNC
Primary source
HGNC:HGNC:29996
See related
Ensembl:ENSG00000179271 MIM:605162
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PRG6; CRIF1; PLINP; CKBBP2; Plinp1; MRP-L59; PLINP-1; CKbetaBP2
Summary
This gene encodes a nuclear-localized protein that may be induced by p53 and regulates the cell cycle by inhibiting G1 to S phase progression. The encoded protein may interact with other cell cycle regulators. [provided by RefSeq, Aug 2012]
Expression
Ubiquitous expression in kidney (RPKM 22.3), fat (RPKM 19.9) and 25 other tissues See more
Orthologs

Genomic context

See GADD45GIP1 in Genome Data Viewer
Location:
19p13.13
Exon count:
2
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (12953119..12957223, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (13064970..13068068, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 7930 Neighboring gene phenylalanyl-tRNA synthetase subunit alpha Neighboring gene microRNA 6515 Neighboring gene calreticulin Neighboring gene RAD23 homolog A, nucleotide excision repair protein Neighboring gene DAN domain BMP antagonist family member 5 Neighboring gene uncharacterized LOC107985286 Neighboring gene nuclear factor I X

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC4667, MGC4758

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
mitochondrial translational elongation TAS
Traceable Author Statement
more info
 
mitochondrial translational termination TAS
Traceable Author Statement
more info
 
mitotic cell cycle arrest IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitotic cell cycle arrest IDA
Inferred from Direct Assay
more info
PubMed 
viral process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
mitochondrial matrix TAS
Traceable Author Statement
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
ribosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
growth arrest and DNA damage-inducible proteins-interacting protein 1
Names
39S ribosomal protein L59, mitochondrial
CKII beta binding protein 2
CKII beta-associating protein
CR6 interacting factor 1
growth arrest and DNA-damage-inducible, gamma interacting protein 1
growth arrest- and DNA damage-inducible GADD45G-interacting protein
mitochondrial large ribosomal subunit protein CRIF1
mitochondrial large ribosomal subunit protein mL64
p53-responsive gene 6 protein
papillomavirus L2 interacting nuclear protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_052850.4NP_443082.2  growth arrest and DNA damage-inducible proteins-interacting protein 1

    See identical proteins and their annotated locations for NP_443082.2

    Status: REVIEWED

    Source sequence(s)
    AC092069, AF479749, AI309741
    Consensus CDS
    CCDS12290.1
    UniProtKB/Swiss-Prot
    Q8TAE8
    Related
    ENSP00000323065.1, ENST00000316939.3
    Conserved Domains (1) summary
    pfam10147
    Location:48190
    CR6_interact; Growth arrest and DNA-damage-inducible proteins-interacting protein 1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    12953119..12957223 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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