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TAAR5 trace amine associated receptor 5 [ Homo sapiens (human) ]

Gene ID: 9038, updated on 27-Nov-2024

Summary

Official Symbol
TAAR5provided by HGNC
Official Full Name
trace amine associated receptor 5provided by HGNC
Primary source
HGNC:HGNC:30236
See related
Ensembl:ENSG00000135569 MIM:607405; AllianceGenome:HGNC:30236
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PNR; taR-5
Summary
Enables trimethylamine receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and cognition. Is active in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See TAAR5 in Genome Data Viewer
Location:
6q23.2
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (132588592..132616747, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (133783556..133811705, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (132909731..132937886, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene trace amine associated receptor 7, pseudogene Neighboring gene trace amine associated receptor 6 Neighboring gene trace amine associated receptor 4, pseudogene Neighboring gene trace amine associated receptor 3, pseudogene Neighboring gene trace amine associated receptor 2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17551 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17552 Neighboring gene trace amine associated receptor 1

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Markers

Clone Names

  • MGC138414, MGC138416

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity TAS
Traceable Author Statement
more info
PubMed 
enables trace-amine receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables trimethylamine receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cognition ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in sensory perception of smell ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in signal transduction TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
trace amine-associated receptor 5
Names
putative neurotransmitter receptor
trace amine receptor 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001389527.1NP_001376456.1  trace amine-associated receptor 5

    Status: VALIDATED

    Source sequence(s)
    AL513524
    Consensus CDS
    CCDS5156.1
    UniProtKB/Swiss-Prot
    D8KZS1, O14804, Q2M1V1, Q4VBL1, Q5VUQ3, Q6NTA8
    Conserved Domains (1) summary
    cd15318
    Location:35316
    7tmA_TAAR5; trace amine-associated receptor 5, member of the class A family of seven-transmembrane G protein-coupled receptors
  2. NM_003967.3NP_003958.2  trace amine-associated receptor 5

    See identical proteins and their annotated locations for NP_003958.2

    Status: VALIDATED

    Source sequence(s)
    AL513524
    Consensus CDS
    CCDS5156.1
    UniProtKB/Swiss-Prot
    D8KZS1, O14804, Q2M1V1, Q4VBL1, Q5VUQ3, Q6NTA8
    Related
    ENSP00000258034.2, ENST00000258034.4
    Conserved Domains (1) summary
    cd15318
    Location:35316
    7tmA_TAAR5; trace amine-associated receptor 5, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    132588592..132616747 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    133783556..133811705 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)