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FAM110B family with sequence similarity 110 member B [ Homo sapiens (human) ]

Gene ID: 90362, updated on 15-Jun-2019

Summary

Official Symbol
FAM110Bprovided by HGNC
Official Full Name
family with sequence similarity 110 member Bprovided by HGNC
Primary source
HGNC:HGNC:28587
See related
Ensembl:ENSG00000169122 MIM:611394
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C8orf72
Expression
Broad expression in spleen (RPKM 2.9), brain (RPKM 1.5) and 19 other tissues See more
Orthologs

Genomic context

See FAM110B in Genome Data Viewer
Location:
8q12.1
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 8 NC_000008.11 (57994509..58149718)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (58907068..59062277)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375856 Neighboring gene long intergenic non-protein coding RNA 1602 Neighboring gene ribosomal protein L26 pseudogene 26 Neighboring gene uncharacterized LOC107986945 Neighboring gene VISTA enhancer hs1364 Neighboring gene uncharacterized LOC101929528

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.
NHGRI GWA Catalog
Genome-wide association study identifies 8 novel loci associated with blood pressure responses to interventions in Han Chinese.
NHGRI GWA Catalog
Genome-Wide Association Study of Primary Dentition Pit-and-Fissure and Smooth Surface Caries.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC39325

Gene Ontology Provided by GOA

Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
 
microtubule organizing center IEA
Inferred from Electronic Annotation
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_147189.3NP_671722.1  protein FAM110B

    See identical proteins and their annotated locations for NP_671722.1

    Status: VALIDATED

    Source sequence(s)
    AC104350, AC110013, AK092221
    Consensus CDS
    CCDS6170.1
    UniProtKB/Swiss-Prot
    Q8TC76
    UniProtKB/TrEMBL
    A0A024R7V5, B3KRT5
    Related
    ENSP00000355204.3, ENST00000361488.7
    Conserved Domains (2) summary
    pfam14160
    Location:253361
    FAM110_C; Centrosome-associated C terminus
    pfam14161
    Location:13118
    FAM110_N; Centrosome-associated N terminus

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    57994509..58149708
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005251324.3XP_005251381.1  protein FAM110B isoform X1

    See identical proteins and their annotated locations for XP_005251381.1

    UniProtKB/Swiss-Prot
    Q8TC76
    UniProtKB/TrEMBL
    A0A024R7V5
    Conserved Domains (2) summary
    pfam14160
    Location:253361
    FAM110_C; Centrosome-associated C terminus
    pfam14161
    Location:13118
    FAM110_N; Centrosome-associated N terminus
  2. XM_017013948.1XP_016869437.1  protein FAM110B isoform X1

    UniProtKB/Swiss-Prot
    Q8TC76
    UniProtKB/TrEMBL
    A0A024R7V5
    Conserved Domains (2) summary
    pfam14160
    Location:253361
    FAM110_C; Centrosome-associated C terminus
    pfam14161
    Location:13118
    FAM110_N; Centrosome-associated N terminus
  3. XM_005251325.3XP_005251382.1  protein FAM110B isoform X1

    See identical proteins and their annotated locations for XP_005251382.1

    UniProtKB/Swiss-Prot
    Q8TC76
    UniProtKB/TrEMBL
    A0A024R7V5
    Conserved Domains (2) summary
    pfam14160
    Location:253361
    FAM110_C; Centrosome-associated C terminus
    pfam14161
    Location:13118
    FAM110_N; Centrosome-associated N terminus
  4. XM_005251326.3XP_005251383.1  protein FAM110B isoform X1

    See identical proteins and their annotated locations for XP_005251383.1

    UniProtKB/Swiss-Prot
    Q8TC76
    UniProtKB/TrEMBL
    A0A024R7V5
    Conserved Domains (2) summary
    pfam14160
    Location:253361
    FAM110_C; Centrosome-associated C terminus
    pfam14161
    Location:13118
    FAM110_N; Centrosome-associated N terminus
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