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TP53I13 tumor protein p53 inducible protein 13 [ Homo sapiens (human) ]

Gene ID: 90313, updated on 21-Dec-2019

Summary

Official Symbol
TP53I13provided by HGNC
Official Full Name
tumor protein p53 inducible protein 13provided by HGNC
Primary source
HGNC:HGNC:25102
See related
Ensembl:ENSG00000167543
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DSCP1
Expression
Ubiquitous expression in fat (RPKM 17.1), spleen (RPKM 12.9) and 25 other tissues See more
Orthologs

Genomic context

See TP53I13 in Genome Data Viewer
Location:
17q11.2
Exon count:
9
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (29567180..29573157)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (27894198..27900175)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene TAO kinase 1 Neighboring gene RNA, U6 small nuclear 1034, pseudogene Neighboring gene abhydrolase domain containing 15 Neighboring gene GIT ArfGAP 1 Neighboring gene ankyrin repeat domain 13B Neighboring gene coronin 6

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
negative regulation of cell cycle IDA
Inferred from Direct Assay
more info
PubMed 
response to UV IEP
Inferred from Expression Pattern
more info
PubMed 
response to drug IEP
Inferred from Expression Pattern
more info
PubMed 
response to organic cyclic compound IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
tumor protein p53-inducible protein 13
Names
damage-stimulated cytoplasmic protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001346077.1NP_001333006.1  tumor protein p53-inducible protein 13 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2 and 3 both encode isoform b.
    Source sequence(s)
    AC104564
    UniProtKB/TrEMBL
    A0A024QZ67
  2. NM_001346078.1NP_001333007.1  tumor protein p53-inducible protein 13 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2 and 3 both encode isoform b.
    Source sequence(s)
    AC104564
    UniProtKB/TrEMBL
    A0A024QZ67
  3. NM_001346079.2NP_001333008.1  tumor protein p53-inducible protein 13 isoform c precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (c) has the same N- and C-termini but is shorter compared to isoform a.
    Source sequence(s)
    AC104564
  4. NM_001346081.2NP_001333010.1  tumor protein p53-inducible protein 13 isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks an alternate exon and uses an alternate splice junction compared to variant 1. The resulting isoform (d) is shorter at the N-terminus compared to isoform a. Variants 5 and 6 both encode the same isoform (d).
    Source sequence(s)
    AC104564
  5. NM_001346082.1NP_001333011.1  tumor protein p53-inducible protein 13 isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) has an alternate 5' end, lacks an alternate exon, and uses an alternate splice junction compared to variant 1. The resulting isoform (d) is shorter at the N-terminus compared to isoform a. Variants 5 and 6 both encode the same isoform (d).
    Source sequence(s)
    AC104564
  6. NM_138349.4NP_612358.3  tumor protein p53-inducible protein 13 isoform a precursor

    See identical proteins and their annotated locations for NP_612358.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (a).
    Source sequence(s)
    AL551604, BC001593
    Consensus CDS
    CCDS42289.1
    UniProtKB/Swiss-Prot
    Q8NBR0
    Related
    ENSP00000301057.7, ENST00000301057.8

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    29567180..29573157
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024451016.1XP_024306784.1  tumor protein p53-inducible protein 13 isoform X1

  2. XM_024451018.1XP_024306786.1  tumor protein p53-inducible protein 13 isoform X2

  3. XM_024451017.1XP_024306785.1  tumor protein p53-inducible protein 13 isoform X1

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