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ZNF30 zinc finger protein 30 [ Homo sapiens (human) ]

Gene ID: 90075, updated on 13-Mar-2020

Summary

Official Symbol
ZNF30provided by HGNC
Official Full Name
zinc finger protein 30provided by HGNC
Primary source
HGNC:HGNC:13090
See related
Ensembl:ENSG00000168661
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KOX28
Expression
Ubiquitous expression in brain (RPKM 1.2), prostate (RPKM 1.2) and 25 other tissues See more
Orthologs

Genomic context

See ZNF30 in Genome Data Viewer
Location:
19q13.11
Exon count:
9
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (34923795..34945172)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (35417807..35436076)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 904 Neighboring gene uncharacterized LOC105372377 Neighboring gene long intergenic non-protein coding RNA 1838 Neighboring gene ZNF30 antisense RNA 1 Neighboring gene zinc finger protein 792 Neighboring gene GRAM domain containing 1A

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20562, DKFZp686N19164

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 30
Names
zinc finger protein 30 (KOX 28)
zinc finger protein KOX28

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001099437.2NP_001092907.1  zinc finger protein 30 isoform a

    See identical proteins and their annotated locations for NP_001092907.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (a).
    Source sequence(s)
    AK000569, BC142996, DC352784
    Consensus CDS
    CCDS46044.1
    UniProtKB/Swiss-Prot
    P17039
    Related
    ENSP00000303889.7, ENST00000303586.11
    Conserved Domains (5) summary
    smart00349
    Location:1475
    KRAB; krueppel associated box
    COG5048
    Location:245624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:403423
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:304327
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001099438.1NP_001092908.1  zinc finger protein 30 isoform a

    See identical proteins and their annotated locations for NP_001092908.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 encode the same isoform.
    Source sequence(s)
    AC008555, AK000569, BC142996, DA554380, DC352784
    Consensus CDS
    CCDS46044.1
    UniProtKB/Swiss-Prot
    P17039
    Related
    ENSP00000403441.1, ENST00000439785.5
    Conserved Domains (5) summary
    smart00349
    Location:1475
    KRAB; krueppel associated box
    COG5048
    Location:245624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:403423
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:304327
    zf-H2C2_2; Zinc-finger double domain
  3. NM_194325.3NP_919306.2  zinc finger protein 30 isoform b

    See identical proteins and their annotated locations for NP_919306.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The encoded protein (isoform b) is shorter than isoform a.
    Source sequence(s)
    AK000569, BC142996, DA504398, DC352784
    Consensus CDS
    CCDS46045.1
    UniProtKB/Swiss-Prot
    P17039
    Related
    ENSP00000469954.1, ENST00000601142.1
    Conserved Domains (5) summary
    smart00349
    Location:1474
    KRAB; krueppel associated box
    COG5048
    Location:244623
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:402422
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:303326
    zf-H2C2_2; Zinc-finger double domain

RNA

  1. NR_024018.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) uses two alternate splice sites and includes an additional exon, compared to variant 1. This variant is believed to be non-coding since translation from the 5'-most translation start codon, as used by variant 1, would cause nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AK000569, AK290435, DC314501
    Related
    ENST00000601957.5

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    34923795..34945172
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017027424.1XP_016882913.1  zinc finger protein 30 isoform X1

    UniProtKB/Swiss-Prot
    P17039
    Conserved Domains (5) summary
    smart00349
    Location:1475
    KRAB; krueppel associated box
    COG5048
    Location:245624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:403423
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:304327
    zf-H2C2_2; Zinc-finger double domain
  2. XM_017027426.1XP_016882915.1  zinc finger protein 30 isoform X2

    UniProtKB/Swiss-Prot
    P17039
    Conserved Domains (5) summary
    smart00349
    Location:1474
    KRAB; krueppel associated box
    COG5048
    Location:244623
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:402422
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:303326
    zf-H2C2_2; Zinc-finger double domain
  3. XM_017027425.1XP_016882914.1  zinc finger protein 30 isoform X2

    UniProtKB/Swiss-Prot
    P17039
    Conserved Domains (5) summary
    smart00349
    Location:1474
    KRAB; krueppel associated box
    COG5048
    Location:244623
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:402422
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:303326
    zf-H2C2_2; Zinc-finger double domain
  4. XM_017027428.1XP_016882917.1  zinc finger protein 30 isoform X3

    UniProtKB/Swiss-Prot
    P17039
    Conserved Domains (3) summary
    COG5048
    Location:163542
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:321341
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:222245
    zf-H2C2_2; Zinc-finger double domain
  5. XM_011527443.2XP_011525745.1  zinc finger protein 30 isoform X1

    See identical proteins and their annotated locations for XP_011525745.1

    UniProtKB/Swiss-Prot
    P17039
    Conserved Domains (5) summary
    smart00349
    Location:1475
    KRAB; krueppel associated box
    COG5048
    Location:245624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:403423
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:304327
    zf-H2C2_2; Zinc-finger double domain
  6. XM_011527444.1XP_011525746.1  zinc finger protein 30 isoform X1

    See identical proteins and their annotated locations for XP_011525746.1

    UniProtKB/Swiss-Prot
    P17039
    Conserved Domains (5) summary
    smart00349
    Location:1475
    KRAB; krueppel associated box
    COG5048
    Location:245624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:403423
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:304327
    zf-H2C2_2; Zinc-finger double domain
  7. XM_017027423.1XP_016882912.1  zinc finger protein 30 isoform X1

    UniProtKB/Swiss-Prot
    P17039
    Conserved Domains (5) summary
    smart00349
    Location:1475
    KRAB; krueppel associated box
    COG5048
    Location:245624
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:403423
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:304327
    zf-H2C2_2; Zinc-finger double domain
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