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hypA hydrogenase/urease nickel incorporation protein HypA [ Helicobacter pylori 26695 ]

Gene ID: 899398, discontinued on 23-Mar-2020
  • This record was discontinued.
Gene symbol
hypA
Gene description
hydrogenase/urease nickel incorporation protein HypA
Locus tag
HP_RS04240
Gene type
protein coding
Organism
Helicobacter pylori 26695 (strain: 26695)
Lineage
Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; Helicobacteraceae; Helicobacter
Old locus tag
HP0869; HP_0869
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Genomic Sequence:
NC_000915.1

Go to nucleotide: Graphics FASTA GenBank

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The data are interpreted in terms of a proposed mechanism wherein HypA and UreE2 act as co-metallochaperones that target the delivery of Ni(2+) to apo-urease with high fidelity.
    Title: The Helicobacter pylori HypA·UreE(2) Complex Contains a Novel High-Affinity Ni(II)-Binding Site.
  2. the role of the N-terminal amine in Ni binding of HypA
    Title: Nickel Ligation of the N-Terminal Amine of HypA Is Required for Urease Maturation in Helicobacter pylori.
  3. a HypA zinc site has an essential role in acid viability and proper urease maturation in Helicobacter pylori
    Title: Dynamic HypA zinc site is essential for acid viability and proper urease maturation in Helicobacter pylori.
  4. HypA, UreE and UreG cannot form a heterotrimeric protein complex in vitro; instead, HypA and UreG compete with each other for UreE recognition.
    Title: Helicobacter pylori hydrogenase accessory protein HypA and urease accessory protein UreG compete with each other for UreE recognition.
  5. The unique N terminus of H. pylori HypB was identified to participate in the interaction with H. pylori HypA.
    Title: Metallo-GTPase HypB from Helicobacter pylori and its interaction with nickel chaperone protein HypA.
Submit: New GeneRIF Correction
Preferred Names
hydrogenase/urease nickel incorporation protein HypA

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000915.1 Reference assembly

    Range
    920005..920358 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_000545280.1 hydrogenase/urease nickel incorporation protein HypA [Helicobacter pylori]

    See identical proteins and their annotated locations for WP_000545280.1

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0A0U4.1