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KBTBD6 kelch repeat and BTB domain containing 6 [ Homo sapiens (human) ]

Gene ID: 89890, updated on 17-Jun-2019

Summary

Official Symbol
KBTBD6provided by HGNC
Official Full Name
kelch repeat and BTB domain containing 6provided by HGNC
Primary source
HGNC:HGNC:25340
See related
Ensembl:ENSG00000165572 MIM:617738
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Orthologs

Genomic context

See KBTBD6 in Genome Data Viewer
Location:
13q14.11
Exon count:
1
Annotation release Status Assembly Chr Location
109.20190607 current GRCh38.p13 (GCF_000001405.39) 13 NC_000013.11 (41127569..41132802, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (41701709..41706936, complement)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene microRNA 3168 Neighboring gene RNA, 7SL, cytoplasmic 597, pseudogene Neighboring gene uncharacterized LOC101929140 Neighboring gene calmodulin 2 pseudogene 3 Neighboring gene kelch repeat and BTB domain containing 7

Genomic regions, transcripts, and products

Pathways from BioSystems

  • Adaptive Immune System, organism-specific biosystem (from REACTOME)
    Adaptive Immune System, organism-specific biosystemAdaptive immunity refers to antigen-specific immune response efficiently involved in clearing the pathogens. The adaptive immune system is comprised of B and T lymphocytes that express receptors with...
  • Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem (from REACTOME)
    Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystemIntracellular foreign or aberrant host proteins are cleaved into peptide fragments of a precise size, such that they can be loaded on to class I MHC molecules and presented externally to cytotoxic T ...
  • Class I MHC mediated antigen processing & presentation, organism-specific biosystem (from REACTOME)
    Class I MHC mediated antigen processing & presentation, organism-specific biosystemMajor histocompatibility complex (MHC) class I molecules play an important role in cell mediated immunity by reporting on intracellular events such as viral infection, the presence of intracellular b...
  • Immune System, organism-specific biosystem (from REACTOME)
    Immune System, organism-specific biosystemHumans are exposed to millions of potential pathogens daily, through contact, ingestion, and inhalation. Our ability to avoid infection depends on the adaptive immune system and during the first crit...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ58260, DKFZp547M073, DKFZp547E1912

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
post-translational protein modification TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
cytosol TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
kelch repeat and BTB domain-containing protein 6
Names
kelch repeat and BTB (POZ) domain containing 6

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152903.5NP_690867.3  kelch repeat and BTB domain-containing protein 6

    See identical proteins and their annotated locations for NP_690867.3

    Status: VALIDATED

    Source sequence(s)
    AL354696
    Consensus CDS
    CCDS9376.1
    UniProtKB/Swiss-Prot
    Q86V97
    Related
    ENSP00000368799.1, ENST00000379485.1
    Conserved Domains (2) summary
    sd00038
    Location:425471
    Kelch; KELCH repeat [structural motif]
    cl28614
    Location:55553
    BTB; Broad-Complex, Tramtrack and Bric a brac

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p13 Primary Assembly

    Range
    41127569..41132802 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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