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NAV2 neuron navigator 2 [ Homo sapiens (human) ]

Gene ID: 89797, updated on 17-Jun-2024

Summary

Official Symbol
NAV2provided by HGNC
Official Full Name
neuron navigator 2provided by HGNC
Primary source
HGNC:HGNC:15997
See related
Ensembl:ENSG00000166833 MIM:607026; AllianceGenome:HGNC:15997
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HELAD1; RAINB1; POMFIL2; UNC53H2; STEERIN2
Summary
This gene encodes a member of the neuron navigator gene family, which may play a role in cellular growth and migration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Expression
Broad expression in thyroid (RPKM 4.0), brain (RPKM 3.3) and 25 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See NAV2 in Genome Data Viewer
Location:
11p15.1
Exon count:
47
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (19345236..20121601)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (19465285..20242238)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (19366783..20143147)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene MED14-independent group 3 enhancer GRCh37_chr11:19253866-19255065 Neighboring gene CSRP3 and E2F8 antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3198 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4515 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:19263697-19264268 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:19264269-19264838 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:19290948-19291137 Neighboring gene Sharpr-MPRA regulatory region 11719 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4516 Neighboring gene E2F transcription factor 8 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4517 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4518 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3199 Neighboring gene proliferating cell nuclear antigen pseudogene 4 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:19416525-19417056 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4519 Neighboring gene MPRA-validated peak1231 silencer Neighboring gene RNA, 5S ribosomal pseudogene 335 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr11:19463438-19464637 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4521 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4522 Neighboring gene NAV2 antisense RNA 5 Neighboring gene NAV2 antisense RNA 4 Neighboring gene small nucleolar RNA SNORA1 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_19823 Neighboring gene microRNA 4486 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4523 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr11:19691725-19692246 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_19830 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:19719279-19719442 Neighboring gene NANOG hESC enhancer GRCh37_chr11:19722632-19723146 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:19725055-19725555 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:19724554-19725054 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:19734258-19734451 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:19768963-19769464 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:19778561-19779113 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:19793703-19794210 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:19794211-19794719 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3201 Neighboring gene lncRNA enhancing IL-6/STAT3 signaling activation 1 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:19842672-19843172 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:19843173-19843673 Neighboring gene microRNA 4694 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr11:19913575-19914774 Neighboring gene Sharpr-MPRA regulatory region 6685 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4524 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr11:20000027-20001226 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:20021347-20022216 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:20022217-20023085 Neighboring gene uncharacterized LOC124902644 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:20046732-20047316 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:20048270-20048921 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:20048922-20049572 Neighboring gene NAV2 antisense RNA 3 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr11:20070019-20071218 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:20086241-20087043 Neighboring gene NAV2 antisense RNA 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:20133119-20134018 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:20134019-20134918 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:20135723-20136224 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:20136225-20136724 Neighboring gene uncharacterized LOC107984418 Neighboring gene uncharacterized LOC124902643 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr11:20177816-20179015 Neighboring gene developing brain homeobox 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

EBI GWAS Catalog

Description
Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder.
EBI GWAS Catalog
Genomewide association study for determinants of HIV-1 acquisition and viral set point in HIV-1 serodiscordant couples with quantified virus exposure.
EBI GWAS Catalog
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ10633, FLJ11030, FLJ23707, FLJ77876, KIAA1419

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables 3'-5' DNA helicase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables heparin binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in DNA duplex unwinding IEA
Inferred from Electronic Annotation
more info
 
involved_in glossopharyngeal nerve development IEA
Inferred from Electronic Annotation
more info
 
involved_in locomotory behavior IEA
Inferred from Electronic Annotation
more info
 
involved_in nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in neurogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in optic nerve development IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of systemic arterial blood pressure by baroreceptor feedback IEA
Inferred from Electronic Annotation
more info
 
involved_in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
 
involved_in sensory perception of sound IEA
Inferred from Electronic Annotation
more info
 
involved_in vagus nerve development IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in interstitial matrix IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
neuron navigator 2
Names
helicase, APC down-regulated 1
pore membrane and/or filament-interacting-like protein 2
retinoic acid inducible gene in neuroblastoma 1
steerin-2
unc-53 homolog 2
NP_001104488.1
NP_001104489.1
NP_001231892.1
NP_660093.2
NP_892009.3
XP_005253271.1
XP_006718427.1
XP_006718428.1
XP_006718429.1
XP_011518746.1
XP_011518747.1
XP_011518748.1
XP_011518749.1
XP_011518750.1
XP_011518751.1
XP_011518752.1
XP_016874009.1
XP_016874010.1
XP_016874011.1
XP_016874013.1
XP_024304526.1
XP_047283765.1
XP_047283766.1
XP_047283767.1
XP_047283768.1
XP_047283769.1
XP_047283770.1
XP_047283771.1
XP_047283772.1
XP_047283773.1
XP_047283774.1
XP_047283775.1
XP_047283776.1
XP_047283777.1
XP_047283778.1
XP_047283779.1
XP_047283780.1
XP_047283781.1
XP_047283782.1
XP_047283783.1
XP_047283784.1
XP_047283785.1
XP_047283786.1
XP_047283787.1
XP_047283789.1
XP_047283790.1
XP_047283791.1
XP_047283792.1
XP_047283793.1
XP_047283794.1
XP_054226346.1
XP_054226347.1
XP_054226348.1
XP_054226349.1
XP_054226350.1
XP_054226351.1
XP_054226352.1
XP_054226353.1
XP_054226354.1
XP_054226355.1
XP_054226356.1
XP_054226357.1
XP_054226358.1
XP_054226359.1
XP_054226360.1
XP_054226361.1
XP_054226362.1
XP_054226363.1
XP_054226364.1
XP_054226365.1
XP_054226366.1
XP_054226367.1
XP_054226368.1
XP_054226369.1
XP_054226370.1
XP_054226371.1
XP_054226372.1
XP_054226373.1
XP_054226374.1
XP_054226375.1
XP_054226376.1
XP_054226377.1
XP_054226378.1
XP_054226379.1
XP_054226380.1
XP_054226381.1
XP_054226382.1
XP_054226383.1
XP_054226384.1
XP_054226385.1
XP_054226386.1
XP_054226387.1
XP_054226388.1
XP_054226389.1
XP_054226390.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_030347.2 RefSeqGene

    Range
    372603..781367
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001111018.2NP_001104488.1  neuron navigator 2 isoform 3

    See identical proteins and their annotated locations for NP_001104488.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) contains an alternate 5' exon and represents use of an alternate promoter, compared to variant 1. It encodes isoform 3, which has a distinct and shorter N-terminus, compared to isoform 5.
    Source sequence(s)
    AC015684, AC090662, AC111163, AC113193
    Consensus CDS
    CCDS53612.1
    UniProtKB/TrEMBL
    A7E2D6
    Related
    ENSP00000353871.4, ENST00000360655.8
    Conserved Domains (5) summary
    smart00382
    Location:20272135
    AAA; ATPases associated with a variety of cellular activities
    cd00014
    Location:22126
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam11235
    Location:151322
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam13401
    Location:20302117
    AAA_22; AAA domain
    pfam15898
    Location:17841836
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
  2. NM_001111019.3NP_001104489.1  neuron navigator 2 isoform 4

    See identical proteins and their annotated locations for NP_001104489.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) has multiple differences, compared to variant 1. These differences result in a distinct 5' UTR and cause translation initiation at an alternate start codon, compared to variant 1. The encoded protein (isoform 4) has a distinct N-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC015684, AK074287, R23148
    Consensus CDS
    CCDS44552.1
    UniProtKB/Swiss-Prot
    Q8IVL1
    Related
    ENSP00000437316.1, ENST00000533917.5
    Conserved Domains (3) summary
    smart00382
    Location:11551263
    AAA; ATPases associated with a variety of cellular activities
    pfam13401
    Location:11581245
    AAA_22; AAA domain
    pfam15898
    Location:912964
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
  3. NM_001244963.2NP_001231892.1  neuron navigator 2 isoform 5

    See identical proteins and their annotated locations for NP_001231892.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) represents the longest transcript and encodes the longest isoform (5).
    Source sequence(s)
    AC009549, AC015684, AC090662, AC111163
    Consensus CDS
    CCDS58126.1
    UniProtKB/Swiss-Prot
    A6NEC1, Q8IVK3, Q8IVK4, Q8IVK5, Q8IVK6, Q8IVK7, Q8IVK8, Q8IVL1, Q8NHC9, Q8NHD0, Q8TDE9, Q8TDF0, Q8TEB3, Q96B30, Q9NUZ6, Q9NVM7, Q9P2C8
    UniProtKB/TrEMBL
    A7E2D6
    Related
    ENSP00000379396.3, ENST00000396087.7
    Conserved Domains (4) summary
    smart00382
    Location:21502258
    AAA; ATPases associated with a variety of cellular activities
    cd00014
    Location:89190
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam13401
    Location:21532240
    AAA_22; AAA domain
    pfam15898
    Location:19071959
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
  4. NM_145117.5NP_660093.2  neuron navigator 2 isoform 2

    See identical proteins and their annotated locations for NP_660093.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks several alternate exons in the coding region, compared to variant 5. This results in a shorter protein (isoform 2), which maintains the reading frame and contains the same N- and C-termimi, compared to isoform 5.
    Source sequence(s)
    AC009549, AC015684, AC090662, AC111163
    Consensus CDS
    CCDS7850.1
    UniProtKB/TrEMBL
    A7E2D6
    Related
    ENSP00000309577.6, ENST00000349880.9
    Conserved Domains (5) summary
    smart00382
    Location:20912199
    AAA; ATPases associated with a variety of cellular activities
    cd00014
    Location:89190
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam11235
    Location:215386
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam13401
    Location:20942181
    AAA_22; AAA domain
    pfam15898
    Location:18481900
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
  5. NM_182964.6NP_892009.3  neuron navigator 2 isoform 1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) lacks several alternate exons in the coding region, compared to variant 5. This results in a shorter protein (isoform 1), which maintains the reading frame and contains the same N- and C-termimi, compared to isoform 5.
    Source sequence(s)
    AC009549, AC015684, AC090662, AC111163
    Consensus CDS
    CCDS7851.2
    UniProtKB/TrEMBL
    A7E2D6
    Related
    ENSP00000379394.1, ENST00000396085.6
    Conserved Domains (5) summary
    smart00382
    Location:20942202
    AAA; ATPases associated with a variety of cellular activities
    cd00014
    Location:89190
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam11235
    Location:215386
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam13401
    Location:20972184
    AAA_22; AAA domain
    pfam15898
    Location:18511903
    PRKG1_interact; cGMP-dependent protein kinase interacting domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    19345236..20121601
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017018520.3XP_016874009.1  neuron navigator 2 isoform X17

    UniProtKB/TrEMBL
    A7E2D6
    Conserved Domains (5) summary
    cd00014
    Location:22126
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam13401
    Location:20842176
    AAA_22; AAA domain
    cl25496
    Location:245674
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    cl25732
    Location:16231895
    SMC_N; RecF/RecN/SMC N terminal domain
    cl28033
    Location:9051257
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
  2. XM_047427824.1XP_047283780.1  neuron navigator 2 isoform X28

    UniProtKB/TrEMBL
    A7E2D6
  3. XM_017018522.2XP_016874011.1  neuron navigator 2 isoform X24

    UniProtKB/TrEMBL
    A7E2D6
  4. XM_047427828.1XP_047283784.1  neuron navigator 2 isoform X32

    UniProtKB/TrEMBL
    A7E2D6
  5. XM_047427830.1XP_047283786.1  neuron navigator 2 isoform X35

    UniProtKB/TrEMBL
    A7E2D6
  6. XM_047427831.1XP_047283787.1  neuron navigator 2 isoform X36

    UniProtKB/TrEMBL
    A7E2D6
  7. XM_024448758.2XP_024304526.1  neuron navigator 2 isoform X17

    UniProtKB/TrEMBL
    A7E2D6
    Conserved Domains (5) summary
    cd00014
    Location:22126
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam13401
    Location:20842176
    AAA_22; AAA domain
    cl25496
    Location:245674
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    cl25732
    Location:16231895
    SMC_N; RecF/RecN/SMC N terminal domain
    cl28033
    Location:9051257
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
  8. XM_047427820.1XP_047283776.1  neuron navigator 2 isoform X24

    UniProtKB/TrEMBL
    A7E2D6
  9. XM_047427825.1XP_047283781.1  neuron navigator 2 isoform X29

    UniProtKB/TrEMBL
    A7E2D6
  10. XM_047427833.1XP_047283789.1  neuron navigator 2 isoform X36

    UniProtKB/TrEMBL
    A7E2D6
  11. XM_011520444.4XP_011518746.1  neuron navigator 2 isoform X1

    UniProtKB/TrEMBL
    A7E2D6
    Conserved Domains (4) summary
    smart00382
    Location:21472255
    AAA; ATPases associated with a variety of cellular activities
    cd00014
    Location:89190
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam13401
    Location:21502237
    AAA_22; AAA domain
    pfam15898
    Location:19041956
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
  12. XM_006718365.5XP_006718428.1  neuron navigator 2 isoform X6

    UniProtKB/TrEMBL
    A7E2D6
    Conserved Domains (4) summary
    smart00382
    Location:21172225
    AAA; ATPases associated with a variety of cellular activities
    cd00014
    Location:89190
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam13401
    Location:21202207
    AAA_22; AAA domain
    pfam15898
    Location:18741926
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
  13. XM_011520446.4XP_011518748.1  neuron navigator 2 isoform X7

    UniProtKB/TrEMBL
    A7E2D6
    Conserved Domains (4) summary
    smart00382
    Location:21142222
    AAA; ATPases associated with a variety of cellular activities
    cd00014
    Location:89190
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam13401
    Location:21172204
    AAA_22; AAA domain
    pfam15898
    Location:18711923
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
  14. XM_011520445.4XP_011518747.1  neuron navigator 2 isoform X2

    UniProtKB/TrEMBL
    A7E2D6
    Conserved Domains (4) summary
    smart00382
    Location:21282236
    AAA; ATPases associated with a variety of cellular activities
    cd00014
    Location:89190
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam13401
    Location:21312218
    AAA_22; AAA domain
    pfam15898
    Location:18851937
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
  15. XM_047427809.1XP_047283765.1  neuron navigator 2 isoform X4

    UniProtKB/TrEMBL
    A7E2D6
  16. XM_047427814.1XP_047283770.1  neuron navigator 2 isoform X13

    UniProtKB/TrEMBL
    A7E2D6
  17. XM_011520449.4XP_011518751.1  neuron navigator 2 isoform X14

    UniProtKB/TrEMBL
    A7E2D6
    Conserved Domains (4) summary
    smart00382
    Location:20922200
    AAA; ATPases associated with a variety of cellular activities
    cd00014
    Location:89190
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam13401
    Location:20952182
    AAA_22; AAA domain
    pfam15898
    Location:18491901
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
  18. XM_011520447.4XP_011518749.1  neuron navigator 2 isoform X8

    UniProtKB/TrEMBL
    A7E2D6
    Conserved Domains (4) summary
    smart00382
    Location:21132221
    AAA; ATPases associated with a variety of cellular activities
    cd00014
    Location:89190
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam13401
    Location:21162203
    AAA_22; AAA domain
    pfam15898
    Location:18701922
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
  19. XM_047427811.1XP_047283767.1  neuron navigator 2 isoform X9

    UniProtKB/TrEMBL
    A7E2D6
  20. XM_011520450.4XP_011518752.1  neuron navigator 2 isoform X19

    UniProtKB/TrEMBL
    A7E2D6
    Conserved Domains (4) summary
    smart00382
    Location:20802188
    AAA; ATPases associated with a variety of cellular activities
    cd00014
    Location:89190
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam13401
    Location:20832170
    AAA_22; AAA domain
    pfam15898
    Location:18371889
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
  21. XM_017018521.3XP_016874010.1  neuron navigator 2 isoform X21

    UniProtKB/TrEMBL
    A7E2D6
  22. XM_006718364.5XP_006718427.1  neuron navigator 2 isoform X3

    UniProtKB/TrEMBL
    A7E2D6
    Conserved Domains (5) summary
    smart00382
    Location:21272235
    AAA; ATPases associated with a variety of cellular activities
    cd00014
    Location:89190
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam11235
    Location:215386
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam13401
    Location:21302217
    AAA_22; AAA domain
    pfam15898
    Location:18841936
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
  23. XM_047427810.1XP_047283766.1  neuron navigator 2 isoform X5

    UniProtKB/TrEMBL
    A7E2D6
  24. XM_047427812.1XP_047283768.1  neuron navigator 2 isoform X11

    UniProtKB/TrEMBL
    A7E2D6
  25. XM_047427813.1XP_047283769.1  neuron navigator 2 isoform X12

    UniProtKB/TrEMBL
    A7E2D6
  26. XM_047427818.1XP_047283774.1  neuron navigator 2 isoform X22

    UniProtKB/TrEMBL
    A7E2D6
  27. XM_047427819.1XP_047283775.1  neuron navigator 2 isoform X23

    UniProtKB/TrEMBL
    A7E2D6
  28. XM_047427815.1XP_047283771.1  neuron navigator 2 isoform X15

    UniProtKB/TrEMBL
    A7E2D6
  29. XM_047427816.1XP_047283772.1  neuron navigator 2 isoform X16

    UniProtKB/TrEMBL
    A7E2D6
  30. XM_047427821.1XP_047283777.1  neuron navigator 2 isoform X25

    UniProtKB/TrEMBL
    A7E2D6
  31. XM_047427823.1XP_047283779.1  neuron navigator 2 isoform X27

    UniProtKB/TrEMBL
    A7E2D6
  32. XM_011520448.4XP_011518750.1  neuron navigator 2 isoform X10

    UniProtKB/TrEMBL
    A7E2D6
    Conserved Domains (4) summary
    smart00382
    Location:21072215
    AAA; ATPases associated with a variety of cellular activities
    cd00014
    Location:46147
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam13401
    Location:21102197
    AAA_22; AAA domain
    pfam15898
    Location:18641916
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
  33. XM_047427817.1XP_047283773.1  neuron navigator 2 isoform X18

    UniProtKB/TrEMBL
    A7E2D6
  34. XM_017018524.3XP_016874013.1  neuron navigator 2 isoform X33

    UniProtKB/TrEMBL
    A7E2D6
  35. XM_006718366.5XP_006718429.1  neuron navigator 2 isoform X20

    UniProtKB/TrEMBL
    A7E2D6
    Conserved Domains (4) summary
    smart00382
    Location:20782186
    AAA; ATPases associated with a variety of cellular activities
    cd00014
    Location:15118
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam13401
    Location:20812168
    AAA_22; AAA domain
    pfam15898
    Location:18351887
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
  36. XM_047427822.1XP_047283778.1  neuron navigator 2 isoform X26

    UniProtKB/TrEMBL
    A7E2D6
  37. XM_047427829.1XP_047283785.1  neuron navigator 2 isoform X34

    UniProtKB/TrEMBL
    A7E2D6
  38. XM_047427826.1XP_047283782.1  neuron navigator 2 isoform X30

    UniProtKB/TrEMBL
    A7E2D6
  39. XM_047427827.1XP_047283783.1  neuron navigator 2 isoform X31

    UniProtKB/TrEMBL
    A7E2D6
  40. XM_047427834.1XP_047283790.1  neuron navigator 2 isoform X37

    UniProtKB/TrEMBL
    A7E2D6
  41. XM_047427835.1XP_047283791.1  neuron navigator 2 isoform X38

    UniProtKB/TrEMBL
    A7E2D6
  42. XM_047427836.1XP_047283792.1  neuron navigator 2 isoform X39

    UniProtKB/TrEMBL
    A7E2D6
  43. XM_047427837.1XP_047283793.1  neuron navigator 2 isoform X40

  44. XM_005253214.5XP_005253271.1  neuron navigator 2 isoform X41

    Conserved Domains (3) summary
    smart00382
    Location:11431251
    AAA; ATPases associated with a variety of cellular activities
    pfam13401
    Location:11461233
    AAA_22; AAA domain
    pfam15898
    Location:900952
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
  45. XM_047427838.1XP_047283794.1  neuron navigator 2 isoform X42

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    19465285..20242238
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054370387.1XP_054226362.1  neuron navigator 2 isoform X17

    UniProtKB/TrEMBL
    A7E2D6
  2. XM_054370399.1XP_054226374.1  neuron navigator 2 isoform X28

    UniProtKB/TrEMBL
    A7E2D6
  3. XM_054370395.1XP_054226370.1  neuron navigator 2 isoform X24

    UniProtKB/TrEMBL
    A7E2D6
  4. XM_054370403.1XP_054226378.1  neuron navigator 2 isoform X32

    UniProtKB/TrEMBL
    A7E2D6
  5. XM_054370407.1XP_054226382.1  neuron navigator 2 isoform X35

    UniProtKB/TrEMBL
    A7E2D6
  6. XM_054370408.1XP_054226383.1  neuron navigator 2 isoform X36

    UniProtKB/TrEMBL
    A7E2D6
  7. XM_054370394.1XP_054226369.1  neuron navigator 2 isoform X24

    UniProtKB/TrEMBL
    A7E2D6
  8. XM_054370400.1XP_054226375.1  neuron navigator 2 isoform X29

    UniProtKB/TrEMBL
    A7E2D6
  9. XM_054370409.1XP_054226384.1  neuron navigator 2 isoform X36

    UniProtKB/TrEMBL
    A7E2D6
  10. XM_054370388.1XP_054226363.1  neuron navigator 2 isoform X18

    UniProtKB/TrEMBL
    A7E2D6
  11. XM_054370371.1XP_054226346.1  neuron navigator 2 isoform X1

    UniProtKB/TrEMBL
    A7E2D6
  12. XM_054370376.1XP_054226351.1  neuron navigator 2 isoform X6

    UniProtKB/TrEMBL
    A7E2D6
  13. XM_054370377.1XP_054226352.1  neuron navigator 2 isoform X7

    UniProtKB/TrEMBL
    A7E2D6
  14. XM_054370372.1XP_054226347.1  neuron navigator 2 isoform X2

    UniProtKB/TrEMBL
    A7E2D6
  15. XM_054370374.1XP_054226349.1  neuron navigator 2 isoform X4

    UniProtKB/TrEMBL
    A7E2D6
  16. XM_054370383.1XP_054226358.1  neuron navigator 2 isoform X13

    UniProtKB/TrEMBL
    A7E2D6
  17. XM_054370384.1XP_054226359.1  neuron navigator 2 isoform X14

    UniProtKB/TrEMBL
    A7E2D6
  18. XM_054370378.1XP_054226353.1  neuron navigator 2 isoform X8

    UniProtKB/TrEMBL
    A7E2D6
  19. XM_054370379.1XP_054226354.1  neuron navigator 2 isoform X9

    UniProtKB/TrEMBL
    A7E2D6
  20. XM_054370389.1XP_054226364.1  neuron navigator 2 isoform X19

    UniProtKB/TrEMBL
    A7E2D6
  21. XM_054370391.1XP_054226366.1  neuron navigator 2 isoform X21

    UniProtKB/TrEMBL
    A7E2D6
  22. XM_054370373.1XP_054226348.1  neuron navigator 2 isoform X3

    UniProtKB/TrEMBL
    A7E2D6
  23. XM_054370375.1XP_054226350.1  neuron navigator 2 isoform X5

    UniProtKB/TrEMBL
    A7E2D6
  24. XM_054370381.1XP_054226356.1  neuron navigator 2 isoform X11

    UniProtKB/TrEMBL
    A7E2D6
  25. XM_054370382.1XP_054226357.1  neuron navigator 2 isoform X12

    UniProtKB/TrEMBL
    A7E2D6
  26. XM_054370392.1XP_054226367.1  neuron navigator 2 isoform X22

    UniProtKB/TrEMBL
    A7E2D6
  27. XM_054370393.1XP_054226368.1  neuron navigator 2 isoform X23

    UniProtKB/TrEMBL
    A7E2D6
  28. XM_054370385.1XP_054226360.1  neuron navigator 2 isoform X15

    UniProtKB/TrEMBL
    A7E2D6
  29. XM_054370386.1XP_054226361.1  neuron navigator 2 isoform X16

    UniProtKB/TrEMBL
    A7E2D6
  30. XM_054370396.1XP_054226371.1  neuron navigator 2 isoform X25

    UniProtKB/TrEMBL
    A7E2D6
  31. XM_054370398.1XP_054226373.1  neuron navigator 2 isoform X27

    UniProtKB/TrEMBL
    A7E2D6
  32. XM_054370380.1XP_054226355.1  neuron navigator 2 isoform X10

    UniProtKB/TrEMBL
    A7E2D6
  33. XM_054370405.1XP_054226380.1  neuron navigator 2 isoform X33

    UniProtKB/TrEMBL
    A7E2D6
  34. XM_054370390.1XP_054226365.1  neuron navigator 2 isoform X20

    UniProtKB/TrEMBL
    A7E2D6
  35. XM_054370397.1XP_054226372.1  neuron navigator 2 isoform X26

    UniProtKB/TrEMBL
    A7E2D6
  36. XM_054370406.1XP_054226381.1  neuron navigator 2 isoform X34

    UniProtKB/TrEMBL
    A7E2D6
  37. XM_054370401.1XP_054226376.1  neuron navigator 2 isoform X30

    UniProtKB/TrEMBL
    A7E2D6
  38. XM_054370402.1XP_054226377.1  neuron navigator 2 isoform X31

    UniProtKB/TrEMBL
    A7E2D6
  39. XM_054370410.1XP_054226385.1  neuron navigator 2 isoform X37

    UniProtKB/TrEMBL
    A7E2D6
  40. XM_054370411.1XP_054226386.1  neuron navigator 2 isoform X38

    UniProtKB/TrEMBL
    A7E2D6
  41. XM_054370404.1XP_054226379.1  neuron navigator 2 isoform X33

    UniProtKB/TrEMBL
    A7E2D6
  42. XM_054370412.1XP_054226387.1  neuron navigator 2 isoform X39

    UniProtKB/TrEMBL
    A7E2D6
  43. XM_054370413.1XP_054226388.1  neuron navigator 2 isoform X40

  44. XM_054370414.1XP_054226389.1  neuron navigator 2 isoform X41

  45. XM_054370415.1XP_054226390.1  neuron navigator 2 isoform X42