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metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 888947, updated on 26-Jun-2025
Gene symbol
metE
Gene description
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
Locus tag
Rv1133c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Sequence:
NC_000962.3 (1259067..1261346, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene 2-methylcitrate dehydratase Neighboring gene methylcitrate synthase PrpC Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene PPE family protein PPE16

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A riboswitch regulates expression of the coenzyme B12-independent methionine synthase in Mycobacterium tuberculosis: implications for differential methionine synthase function in strains H37Rv and CDC1551. Warner DF, et al. J Bacteriol, 2007 May. PMID 17307844, Free PMC Article
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. findings demonstrate that transcription of metE is contrtolled by a B12 riboswitch
    Title: A riboswitch regulates expression of the coenzyme B12-independent methionine synthase in Mycobacterium tuberculosis: implications for differential methionine synthase function in strains H37Rv and CDC1551.
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Homology

Preferred Names
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
NP_215649.1
  • methionine synthase, vitamin-B12 independent isozyme

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    1259067..1261346 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_215649.1 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_215649.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4LTU8
    Conserved Domains (1) summary
    PRK05222
    Location:10 → 758
    PRK05222; 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WK07.1

Gene LinkOut

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