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htrA serine protease HtrA [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 888912, updated on 6-Jun-2024

Summary

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Gene symbol
htrA
Gene description
serine protease HtrA
Locus tag
Rv1223
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
Also known as
degP
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Genomic context

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Sequence:
NC_000962.3 (1365875..1367461)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene ECF RNA polymerase sigma factor SigE Neighboring gene anti-sigma E factor RseA Neighboring gene Sec-independent protein translocase protein TatB Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The crystal structure of an essential high-temperature requirement protein HtrA1 (Rv1223) from Mycobacterium tuberculosis reveals its unique features. Singh KH, et al. Acta Crystallogr D Struct Biol, 2018 Sep 1. PMID 30198900
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The crystal structure of the periplasmic region consisting of a protease domain (PD) and a PDZ domain from an M. tuberculosis HtrA1 mutant (mHtrA1(S387A)) is reported at 2.7 A resolution.
    Title: The crystal structure of an essential high-temperature requirement protein HtrA1 (Rv1223) from Mycobacterium tuberculosis reveals its unique features.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
serine protease HtrA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    1365875..1367461
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_215739.2 serine protease HtrA [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_215739.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0H3M5J1, A0A1R3XXQ7, A0A9P2H723, A0AAE8WK53
    Conserved Domains (1) summary
    TIGR02037
    Location:254 → 522
    degP_htrA_DO; periplasmic serine protease, Do/DeqQ family
Nucleotide Protein
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