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tgs1 diacyglycerol O-acyltransferase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 888841, updated on 6-Oct-2023
Gene symbol
tgs1
Gene description
diacyglycerol O-acyltransferase
Locus tag
Rv3130c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Sequence:
NC_000962.3 (3494975..3496366, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene pseudo Neighboring gene pseudo Neighboring gene NAD(P)H nitroreductase Neighboring gene two component sensor histidine kinase DevS Neighboring gene two component transcriptional regulator DevR

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Identification of a diacylglycerol acyltransferase gene involved in accumulation of triacylglycerol in Mycobacterium tuberculosis under stress. Sirakova TD, et al. Microbiology (Reading), 2006 Sep. PMID 16946266, Free PMC Article
  2. Powerful induction of divergent tgs1-Rv3131 genes in Mycobacterium tuberculosis is mediated by DevR interaction with a high-affinity site and an adjacent cryptic low-affinity site. Chauhan S, et al. J Bacteriol, 2009 Oct. PMID 19648251, Free PMC Article
  3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. DevR interaction with two binding sites is obligatory for synergistic activation of tgs1-Rv3131 promoters.
    Title: Powerful induction of divergent tgs1-Rv3131 genes in Mycobacterium tuberculosis is mediated by DevR interaction with a high-affinity site and an adjacent cryptic low-affinity site.
  2. Disruption of the RV3130c gene reduced triacylglycerol accumulation, complementation restored this function
    Title: Identification of a diacylglycerol acyltransferase gene involved in accumulation of triacylglycerol in Mycobacterium tuberculosis under stress.
Submit: New GeneRIF Correction

Homology

Preferred Names
diacyglycerol O-acyltransferase
NP_217646.1
  • triacylglycerol synthase

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    3494975..3496366 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_217646.1 diacyglycerol O-acyltransferase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_217646.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2I7WBN4
    Conserved Domains (1) summary
    TIGR02946
    Location:4 → 447
    acyl_WS_DGAT; acyltransferase, WS/DGAT/MGAT
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WKC9.1

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