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sigF RNA polymerase sigma factor SigF [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 888727, updated on 6-Oct-2023

Summary

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Gene symbol
sigF
Gene description
RNA polymerase sigma factor SigF
Locus tag
Rv3286c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (3668169..3668954, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene thiosulfate sulfurtransferase SseA Neighboring gene hypothetical protein Neighboring gene bifunctional protein acetyl-/propionyl-CoA carboxylase subunit alpha AccA Neighboring gene anti-sigma factor RsbW Neighboring gene hypothetical protein Neighboring gene transmembrane protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. These data provide evidence that Rv1364c acts an independent SigF regulator that is sensitive to the osmosensory signal, mediating the cross talk of PknD with the SigF regulon.
    Title: Tuning the Mycobacterium tuberculosis Alternative Sigma Factor SigF through the Multidomain Regulator Rv1364c and Osmosensory Kinase Protein Kinase D.
  2. The present study focuses on identification of important residues involved in binding of SigF protein with Usfx, which are essential in the inhibition of transcription initiation and survival of Mtb.
    Title: Macromolecular structure and interaction studies of SigF and Usfx in Mycobacterium tuberculosis.
  3. may be important for survival in the lung
    Title: Examination of Mycobacterium tuberculosis sigma factor mutants using low-dose aerosol infection of guinea pigs suggests a role for SigC in pathogenesis.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
RNA polymerase sigma factor SigF

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    3668169..3668954 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_217803.1 RNA polymerase sigma factor SigF [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_217803.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A654T3P9
    Conserved Domains (1) summary
    PRK07122
    Location:1 → 261
    PRK07122; RNA polymerase sigma factor SigF; Reviewed
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WGI3.1

Gene LinkOut

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Molecular Biology Databases