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sigC ECF RNA polymerase sigma factor SigC [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 888723, updated on 6-Oct-2023

Summary

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Gene symbol
sigC
Gene description
ECF RNA polymerase sigma factor SigC
Locus tag
Rv2069
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (2326944..2327501)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene bifunctional S-adenosyl-L-methionine-precorrin-2 methyl transferase/precorrin-3 methylase Neighboring gene hypothetical protein Neighboring gene beta-lactamase Neighboring gene precorrin-6A reductase Neighboring gene precorrin-4 C(11)-methyltransferase Neighboring gene precorrin-6Y C(5,15)-methyltransferase Neighboring gene oxidoreductase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mycobacterium tuberculosis H37Rv sigC is expressed from two promoters but is not auto-regulatory. Chang A, et al. Tuberculosis (Edinb), 2012 Jan. PMID 22015173
  2. Examination of Mycobacterium tuberculosis sigma factor mutants using low-dose aerosol infection of guinea pigs suggests a role for SigC in pathogenesis. Karls RK, et al. Microbiology (Reading), 2006 Jun. PMID 16735723
  3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Mycobacterium tuberculosis H37Rv sigC is expressed from two promoters but is not auto-regulatory.
    Title: Mycobacterium tuberculosis H37Rv sigC is expressed from two promoters but is not auto-regulatory.
  2. SigC is likely a key regulator of pathogenesis and adaptive survival in the lung and spleen.
    Title: Examination of Mycobacterium tuberculosis sigma factor mutants using low-dose aerosol infection of guinea pigs suggests a role for SigC in pathogenesis.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
ECF RNA polymerase sigma factor SigC
NP_216585.1
  • ECF subfamily

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    2326944..2327501
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_216585.1 ECF RNA polymerase sigma factor SigC [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_216585.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0E8TXE2
    Conserved Domains (1) summary
    PRK09649
    Location:1 → 185
    PRK09649; RNA polymerase sigma factor SigC; Reviewed
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WGH1.1

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