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pknK serine/threonine-protein kinase PknK [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 888659, updated on 6-Jun-2024
Gene symbol
pknK
Gene description
serine/threonine-protein kinase PknK
Locus tag
Rv3080c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Sequence:
NC_000962.3 (3442656..3445988, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene hydroxylaminobenzene mutase Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene HTH-type transcriptional regulator VirS

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Mycobacterium tuberculosis protein kinase K enables growth adaptation through translation control. Malhotra V, et al. J Bacteriol, 2012 Aug. PMID 22661693, Free PMC Article
  2. Mycobacterium tuberculosis protein kinase K confers survival advantage during early infection in mice and regulates growth in culture and during persistent infection: implications for immune modulation. Malhotra V, et al. Microbiology (Reading), 2010 Sep. PMID 20522497, Free PMC Article
  3. The Mycobacterium tuberculosis protein kinase K modulates activation of transcription from the promoter of mycobacterial monooxygenase operon through phosphorylation of the transcriptional regulator VirS. Kumar P, et al. J Biol Chem, 2009 Apr 24. PMID 19251699, Free PMC Article
  4. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  5. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. PknK regulates the expression of a large subset of tRNA genes so that regulation is synchronized with growth phase and cellular energy status.
    Title: Mycobacterium tuberculosis protein kinase K enables growth adaptation through translation control.
  2. PknK confers survival advantage during early infection in mice and regulates growth during persistent infection.
    Title: Mycobacterium tuberculosis protein kinase K confers survival advantage during early infection in mice and regulates growth in culture and during persistent infection: implications for immune modulation.
  3. PknK modulates VirS-mediated stimulation of transcription from the mym promoter
    Title: The Mycobacterium tuberculosis protein kinase K modulates activation of transcription from the promoter of mycobacterial monooxygenase operon through phosphorylation of the transcriptional regulator VirS.
Submit: New GeneRIF Correction

Homology

Preferred Names
serine/threonine-protein kinase PknK
NP_217596.1
  • protein kinase K (STPK K)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    3442656..3445988 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_217596.1 serine/threonine-protein kinase PknK [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_217596.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A9P2HAK4
    Conserved Domains (2) summary
    COG2909
    Location:333 → 1110
    MalT; ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription]
    cd14014
    Location:25 → 284
    STKc_PknB_like; Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WI65.1

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