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sigL ECF RNA polymerase sigma factor SigL [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 888609, updated on 6-Oct-2023

Summary

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Gene symbol
sigL
Gene description
ECF RNA polymerase sigma factor SigL
Locus tag
Rv0735
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (827543..828076)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene preprotein translocase SecY Neighboring gene adenylate kinase Neighboring gene methionine aminopeptidase Neighboring gene anti-sigma-L factor RslA Neighboring gene transcriptional regulator

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Mycobacterium tuberculosis extracytoplasmic-function sigma factor SigL regulates polyketide synthases and secreted or membrane proteins and is required for virulence. Hahn MY, et al. J Bacteriol, 2005 Oct. PMID 16199577, Free PMC Article
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. In an in vivo murine infection model, the sigL mutant strain showed marked attenuation, indicating that the sigL regulon is important in M. tuberculosis pathogenesis.
    Title: The Mycobacterium tuberculosis extracytoplasmic-function sigma factor SigL regulates polyketide synthases and secreted or membrane proteins and is required for virulence.
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General gene information

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Homology

General protein information

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Preferred Names
ECF RNA polymerase sigma factor SigL
NP_215249.1
  • Belongs to the sigma-70 factor family, ECF subfamily.

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    827543..828076
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_215249.1 ECF RNA polymerase sigma factor SigL [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_215249.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4M3F3
    Conserved Domains (1) summary
    PRK09645
    Location:14 → 177
    PRK09645; ECF RNA polymerase sigma factor SigL
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
6DV9_F.1
6DVB_F.1
6DVC_F.1
6DVD_F.1
P9WGH5.1

Gene LinkOut

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