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sigL ECF RNA polymerase sigma factor SigL [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 888609, updated on 6-Oct-2023
Gene symbol
sigL
Gene description
ECF RNA polymerase sigma factor SigL
Locus tag
Rv0735
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Sequence:
NC_000962.3 (827543..828076)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene preprotein translocase SecY Neighboring gene adenylate kinase Neighboring gene methionine aminopeptidase Neighboring gene anti-sigma-L factor RslA Neighboring gene transcriptional regulator

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. In an in vivo murine infection model, the sigL mutant strain showed marked attenuation, indicating that the sigL regulon is important in M. tuberculosis pathogenesis.
    Title: The Mycobacterium tuberculosis extracytoplasmic-function sigma factor SigL regulates polyketide synthases and secreted or membrane proteins and is required for virulence.
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Homology

Preferred Names
ECF RNA polymerase sigma factor SigL
NP_215249.1
  • Belongs to the sigma-70 factor family, ECF subfamily.

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    827543..828076
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_215249.1 ECF RNA polymerase sigma factor SigL [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_215249.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4M3F3
    Conserved Domains (1) summary
    PRK09645
    Location:14 → 177
    PRK09645; ECF RNA polymerase sigma factor SigL
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
6DV9_F.1
6DVB_F.1
6DVC_F.1
6DVD_F.1
P9WGH5.1

Gene LinkOut

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