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PE_PGRS47 PE-PGRS family protein PE_PGRS47 [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 888339, updated on 15-Jan-2022
Gene symbol
PE_PGRS47
Gene description
PE-PGRS family protein PE_PGRS47
Locus tag
Rv2741
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Sequence:
NC_000962.3 (3053914..3055491)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene transferase Neighboring gene epoxide hydrolase Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Suppression of autophagy and antigen presentation by Mycobacterium tuberculosis PE_PGRS47. Saini NK, et al. Nat Microbiol, 2016 Aug 15. PMID 27562263, Free PMC Article
  2. Mycobacterium tuberculosis PE_PGRS20 and PE_PGRS47 Proteins Inhibit Autophagy by Interaction with Rab1A. Strong EJ, et al. mSphere, 2021 Aug 25. PMID 34346699, Free PMC Article
  3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Mycobacterium tuberculosis PE_PGRS20 and PE_PGRS47 Proteins Inhibit Autophagy by Interaction with Rab1A.
    Title: Mycobacterium tuberculosis PE_PGRS20 and PE_PGRS47 Proteins Inhibit Autophagy by Interaction with Rab1A.
  2. The findings identify PE_PGRS47 as a functionally relevant, non-redundant bacterial factor in the modulation of innate and adaptive immunity by Mycobacterium tuberculosis
    Title: Suppression of autophagy and antigen presentation by Mycobacterium tuberculosis PE_PGRS47.
Submit: New GeneRIF Correction

Homology

Preferred Names
PE-PGRS family protein PE_PGRS47
YP_177902.1
  • Member of the M. tuberculosis PE family. This region is a possible MT-complex-specific genomic island (See Becq et al., 2007 PMID:17545187).

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    3053914..3055491
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_177902.1 PE-PGRS family protein PE_PGRS47 [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for YP_177902.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q79FB3
    Conserved Domains (1) summary
    pfam00934
    Location:1 → 83
    PE; PE family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q79FB3.1

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