U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Rv0678 hypothetical protein [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 888235, updated on 6-Oct-2023

Summary

Go to the top of the page Help
Gene symbol
Rv0678
Gene description
hypothetical protein
Locus tag
Rv0678
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000962.3 (778990..779487)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene enoyl-CoA hydratase EchA5 Neighboring gene transmembrane transport protein MmpL5 Neighboring gene membrane protein MmpS5 Neighboring gene hypothetical protein Neighboring gene transmembrane protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Mutations in rv0678 Confer Low-Level Resistance to Benzothiazinone DprE1 Inhibitors in Mycobacterium tuberculosis. Poulton NC, et al. Antimicrob Agents Chemother, 2022 Sep 20. PMID 35920665, Free PMC Article
  2. Impact of Rv0678 mutations on patients with drug-resistant TB treated with bedaquiline. Kaniga K, et al. Int J Tuberc Lung Dis, 2022 Jun 1. PMID 35650698, Free PMC Article
  3. Bedaquiline-Resistant Tuberculosis Associated with Rv0678 Mutations. Omar SV, et al. N Engl J Med, 2022 Jan 6. PMID 34986292
  4. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  5. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Mutations in rv0678 Confer Low-Level Resistance to Benzothiazinone DprE1 Inhibitors in Mycobacterium tuberculosis.
    Title: Mutations in rv0678 Confer Low-Level Resistance to Benzothiazinone DprE1 Inhibitors in Mycobacterium tuberculosis.
  2. Impact of Rv0678 mutations on patients with drug-resistant TB treated with bedaquiline.
    Title: Impact of Rv0678 mutations on patients with drug-resistant TB treated with bedaquiline.
  3. Bedaquiline-Resistant Tuberculosis Associated with Rv0678 Mutations.
    Title: Bedaquiline-Resistant Tuberculosis Associated with Rv0678 Mutations.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

General protein information

Go to the top of the page Help
Preferred Names
hypothetical protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    778990..779487
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_215192.1 hypothetical protein Rv0678 [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_215192.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A4Y5MWC9, A0A4Y5MYK7
    Conserved Domains (1) summary
    cl21459
    Location:12 → 93
    HTH; Helix-turn-helix domains
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
I6Y8F7.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases