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Rv2459 MFS-type transporter [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 888191, updated on 6-Aug-2024
Gene symbol
Rv2459
Gene description
MFS-type transporter
Locus tag
Rv2459
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Sequence:
NC_000962.3 (2760854..2762380)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene ATP-dependent CLP protease ATP-binding subunit ClpX Neighboring gene homocysteine S-methyltransferase MmuM Neighboring gene ATP-dependent CLP protease proteolytic subunit 2 Neighboring gene ATP-dependent CLP protease proteolytic subunit 1 Neighboring gene trigger factor

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Microarray analysis of efflux pump genes in multidrug-resistant Mycobacterium tuberculosis during stress induced by common anti-tuberculous drugs. Gupta AK, et al. Microb Drug Resist, 2010 Mar. PMID 20001742
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. simultaneous overexpression of efflux pump genes Rv2459, Rv3728, and Rv3065 was associated with resistance to the combination of isoniazid and ethambutol.
    Title: Microarray analysis of efflux pump genes in multidrug-resistant Mycobacterium tuberculosis during stress induced by common anti-tuberculous drugs.
Submit: New GeneRIF Correction

Homology

Preferred Names
MFS-type transporter
NP_216975.1
  • integral membrane transport protein

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    2760854..2762380
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_216975.1 MFS-type transporter [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_216975.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0E8TX39
    Conserved Domains (1) summary
    cd17321
    Location:12 → 437
    MFS_MMR_MDR_like; Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WJW9.1

Gene LinkOut

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Research Materials