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trcR two component transcriptional regulator TrcR [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 887957, updated on 6-Oct-2023
Gene symbol
trcR
Gene description
two component transcriptional regulator TrcR
Locus tag
Rv1033c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Sequence:
NC_000962.3 (1157963..1158736, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene potassium-transporting ATPase subunit B Neighboring gene potassium-transporting ATPase subunit C Neighboring gene two component sensor histidine kinase TrcS Neighboring gene ESAT-6 like protein EsxI Neighboring gene ESAT-6 like protein EsxJ

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The Mycobacterium tuberculosis TrcR response regulator represses transcription of the intracellularly expressed Rv1057 gene, encoding a seven-bladed beta-propeller. Haydel SE, et al. J Bacteriol, 2006 Jan. PMID 16352831, Free PMC Article
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. represses transcription of macrophage expressed Rv1057 gene, encoding a seven-bladed beta-propeller.
    Title: The Mycobacterium tuberculosis TrcR response regulator represses transcription of the intracellularly expressed Rv1057 gene, encoding a seven-bladed beta-propeller.
Submit: New GeneRIF Correction

Homology

Preferred Names
two component transcriptional regulator TrcR
NP_215549.1
  • Note that in vitro autophosphorylation of TrcS requires the presence of Mn2+or Ca2+as a divalent cation cofactor and subsequent transphosphorylation of TrcR is evident in the presence of TrcS-phosphate and Ca2+.

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    1157963..1158736 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_215549.1 two component transcriptional regulator TrcR [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_215549.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4M5F5
    Conserved Domains (1) summary
    COG0745
    Location:33 → 257
    OmpR; DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain [Signal transduction mechanisms, Transcription]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
L7N689.1

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