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vapC30 ribonuclease VapC30 [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 887951, updated on 6-Oct-2023
Gene symbol
vapC30
Gene description
ribonuclease VapC30
Locus tag
Rv0624
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Sequence:
NC_000962.3 (716664..717059)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene membrane protein Neighboring gene membrane protein Neighboring gene antitoxin VapB30 Neighboring gene transmembrane protein Neighboring gene antitoxin VapB5 Neighboring gene ribonuclease VapC5

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides. Lee IG, et al. Nucleic Acids Res, 2015 Sep 3. PMID 26150422, Free PMC Article
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. VapC30 toxin regulates cellular growth through both magnesium and manganese ion-dependent ribonuclease activity and is inhibited by the cognate VapB30 antitoxin.
    Title: Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides.
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Homology

Preferred Names
ribonuclease VapC30
NP_215138.1
  • toxin, part of toxin-antitoxin (TA) operon with Rv0623, contains PIN domain

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    716664..717059
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_215138.1 ribonuclease VapC30 [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_215138.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4LSL8
    Conserved Domains (1) summary
    COG3742
    Location:1 → 130
    COG3742; Uncharacterized protein, contains PIN domain [Function unknown]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WF77.1

Gene LinkOut

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Molecular Biology Databases