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Rv2175c DNA-binding protein [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 887852, updated on 1-May-2025
Gene symbol
Rv2175c
Gene description
DNA-binding protein
Locus tag
Rv2175c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Sequence:
NC_000962.3 (2437446..2437886, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene lipoprotein LppM Neighboring gene hypothetical protein Neighboring gene geranylgeranyl pyrophosphate synthetase IdsA Neighboring gene alpha(1->6)-mannopyranosyltransferase A Neighboring gene serine/threonine-protein kinase PknL Neighboring gene transposase

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The Mycobacterium tuberculosis Ser/Thr kinase substrate Rv2175c is a DNA-binding protein regulated by phosphorylation. Cohen-Gonsaud M, et al. J Biol Chem, 2009 Jul 17. PMID 19457863, Free PMC Article
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data show that the DNA-binding activity was completely abrogated in a Rv2175c_T9D mutant.
    Title: The Mycobacterium tuberculosis Ser/Thr kinase substrate Rv2175c is a DNA-binding protein regulated by phosphorylation.
Submit: New GeneRIF Correction

Homology

Miscellaneous features

  • Loc: c2437866-2437823 mcr5, fragment of putative small regulatory RNA (See DiChiara et al., 2010), cloned from M. bovis BCG Pasteur; ends not mapped,
    82 nt band detected by Northern blot.; Fragment of putative small regulatory RNA
Preferred Names
DNA-binding protein
NP_216691.1
  • A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004 PMID:14766927).

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    2437446..2437886 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_216691.1 DNA-binding protein [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_216691.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0H3MEU8, A0A1R3Y164, A0A9P2H994
    Conserved Domains (2) summary
    pfam18367
    Location:78 → 145
    Rv2175c_C; Rv2175c C-terminal domain of unknown function
    cl21456
    Location:11 → 69
    Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O53509.3

Gene LinkOut

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