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cut4 cutinase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 887610, updated on 6-Aug-2024

Summary

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Gene symbol
cut4
Gene description
cutinase
Locus tag
Rv3452
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
Also known as
clp4; culp4
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Genomic context

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Sequence:
NC_000962.3 (3873452..3874132)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene membrane-anchored mycosin Neighboring gene ESX-4 secretion system protein EccB4 Neighboring gene cutinase Neighboring gene pseudo Neighboring gene tRNA pseudouridine synthase A Neighboring gene 50S ribosomal protein L17

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. B cells response directed against Cut4 and CFP21 lipolytic enzymes in active and latent tuberculosis infections. Rénier W, et al. PLoS One, 2018. PMID 29709002, Free PMC Article
  2. Identification of residues involved in substrate specificity and cytotoxicity of two closely related cutinases from Mycobacterium tuberculosis. Dedieu L, et al. PLoS One, 2013. PMID 23843969, Free PMC Article
  3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. TB reactivation triggers an immune response against these antigens Cut4 and CFP21
    Title: B cells response directed against Cut4 and CFP21 lipolytic enzymes in active and latent tuberculosis infections.
  2. The amino acid residues involved in substrate specificity and cytotoxicity of Cut4 from Mycobacterium tuberculosis have been identified.
    Title: Identification of residues involved in substrate specificity and cytotoxicity of two closely related cutinases from Mycobacterium tuberculosis.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
cutinase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    3873452..3874132
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_217969.1 cutinase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_217969.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    Q7D5I6
    Conserved Domains (1) summary
    cl21494
    Location:47 → 226
    Abhydrolase; alpha/beta hydrolases
Nucleotide Protein
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