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cysG multifunctional uroporphyrin-III C-methyltransferase/precorrin-2 oxidase/ferrochelatase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 887481, updated on 6-Oct-2023

Summary

Gene symbol
cysG
Gene description
multifunctional uroporphyrin-III C-methyltransferase/precorrin-2 oxidase/ferrochelatase
Locus tag
Rv2847c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
Also known as
cysG2
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Genomic context

Sequence:
NC_000962.3 (3154654..3155871, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene proline--tRNA ligase Neighboring gene MFS-type transporter EfpA Neighboring gene cobyrinic acid A,C-diamide synthase Neighboring gene cob(I)alamin adenosyltransferase Neighboring gene magnesium chelatase Neighboring gene GCN5-like N-acetyltransferase

Pathways from PubChem

General protein information

Preferred Names
multifunctional uroporphyrin-III C-methyltransferase/precorrin-2 oxidase/ferrochelatase
NP_215025.2
  • Possible cysG urogen III methylase) (SUMT) (uroporphyrinogen III methylase) (UROM)/precorrin-2 oxidase/ferrochelatase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    3154654..3155871 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_215025.2 multifunctional uroporphyrin-III C-methyltransferase/precorrin-2 oxidase/ferrochelatase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_215025.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A654U1S1
    Conserved Domains (2) summary
    COG1648
    Location:24152
    CysG2; Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme transport and metabolism]
    cd11642
    Location:165394
    SUMT; Uroporphyrin-III C-methyltransferase (also known as S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT)