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hemC porphobilinogen deaminase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 887306, updated on 6-Oct-2023

Summary

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Gene symbol
hemC
Gene description
porphobilinogen deaminase
Locus tag
Rv0510
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (601857..602786)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene transmembrane transport protein MmpL2 Neighboring gene hypothetical protein Neighboring gene glutamyl-tRNA reductase Neighboring gene uroporphyrin-III C-methyltransferase Neighboring gene delta-aminolevulinic acid dehydratase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  2. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  3. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

General protein information

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Preferred Names
porphobilinogen deaminase
NP_215024.1
  • PBG (hydroxymethylbilane synthase) (HMBS) (pre-uroporphyrinogen synthase) Cofactor: covalently binds a dipyrromethane cofactor to which the porphobilinogen subunits are added.

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    601857..602786
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_215024.1 porphobilinogen deaminase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_215024.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0H3L6C0
    Conserved Domains (1) summary
    PRK00072
    Location:1 → 297
    hemC; porphobilinogen deaminase; Reviewed
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WMP3.1

Gene LinkOut

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Molecular Biology Databases