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mpa proteasome-associated ATPase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 887297, updated on 6-Aug-2024
Gene symbol
mpa
Gene description
proteasome-associated ATPase
Locus tag
Rv2115c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Sequence:
NC_000962.3 (2374461..2376290, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene integral membrane protein Neighboring gene hypothetical protein Neighboring gene lipoprotein LppK Neighboring gene hypothetical protein

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex. Kavalchuk M, et al. Nat Commun, 2022 Jan 12. PMID 35022401, Free PMC Article
  2. Fate of pup inside the Mycobacterium proteasome studied by in-cell NMR. Maldonado AY, et al. PLoS One, 2013. PMID 24040288, Free PMC Article
  3. A distinct structural region of the prokaryotic ubiquitin-like protein (Pup) is recognized by the N-terminal domain of the proteasomal ATPase Mpa. Sutter M, et al. FEBS Lett, 2009 Oct 6. PMID 19761766
  4. The proteasome of Mycobacterium tuberculosis is required for resistance to nitric oxide. Darwin KH, et al. Science, 2003 Dec 12. PMID 14671303
  5. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex.
    Title: Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex.
  2. Transient binding of Mpa to the proteasome core particle controls the fate of Pup.
    Title: Fate of pup inside the Mycobacterium proteasome studied by in-cell NMR.
  3. N-terminal coiled-coil domain of Mpa makes extensive contacts along the central region of Pup leaving its N-terminus unconstrained and available for other functional interactions
    Title: A distinct structural region of the prokaryotic ubiquitin-like protein (Pup) is recognized by the N-terminal domain of the proteasomal ATPase Mpa.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Preferred Names
proteasome-associated ATPase

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    2374461..2376290 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_216631.1 proteasome-associated ATPase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_216631.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2I7W8I4
    Conserved Domains (1) summary
    TIGR03689
    Location:54 → 588
    pup_AAA; proteasome ATPase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WQN5.1

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