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pimB alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 887278, updated on 23-Jul-2026
Gene symbol
pimB
Gene description
alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase
Locus tag
Rv2188c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Sequence:
NC_000962.3 (2449993..2451150, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene long-chain-fatty-acid--CoA ligase FadD15 Neighboring gene hypothetical protein Neighboring gene endopeptidase

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Single nucleotide polymorphisms in cell wall biosynthesis-associated genes and phylogeny of Mycobacterium tuberculosis lineages. Chuang PC, et al. Infect Genet Evol, 2010 May. PMID 20223296
  2. Inactivation of Mycobacterium tuberculosis mannosyltransferase pimB reduces the cell wall lipoarabinomannan and lipomannan content and increases the rate of bacterial-induced human macrophage cell death. Torrelles JB, et al. Glycobiology, 2009 Jul. PMID 19318518, Free PMC Article
  3. Inactivation of Corynebacterium glutamicum NCgl0452 and the role of MgtA in the biosynthesis of a novel mannosylated glycolipid involved in lipomannan biosynthesis. Tatituri RVV, et al. J Biol Chem, 2007 Feb 16. PMID 17179146
  4. Compartmentalization of lipid biosynthesis in mycobacteria. Morita YS, et al. J Biol Chem, 2005 Jun 3. PMID 15805104
  5. The pimB gene of Mycobacterium tuberculosis encodes a mannosyltransferase involved in lipoarabinomannan biosynthesis. Schaeffer ML, et al. J Biol Chem, 1999 Oct 29. PMID 10531370

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Preferred Names
alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase
NP_216704.2
  • GDP-mannose-dependent

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    2449993..2451150 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_216704.2 alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_216704.2

    Status: PROVISIONAL

    Conserved Domains (1) summary
    cd03801
    Location:3 → 379
    GT4_PimA-like; phosphatidyl-myo-inositol mannosyltransferase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WMZ3.1

Gene LinkOut

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Research Materials