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dacB2 penicillin-binding protein DacB2 [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 887189, updated on 6-Aug-2024
Gene symbol
dacB2
Gene description
penicillin-binding protein DacB2
Locus tag
Rv2911
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
Also known as
dacB
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Sequence:
NC_000962.3 (3218339..3219214)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene 30S ribosomal protein S16 Neighboring gene hypothetical protein Neighboring gene TetR family HTH-type transcriptional regulator Neighboring gene D-amino acid aminohydrolase

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Double deletion of PknI/DacB2 leads to attenuation of Mycobacterium tuberculosis for growth and virulence. Kandasamy S, et al. Tuberculosis (Edinb), 2020 Jul. PMID 32741534
  2. Deletion and overexpression studies on DacB2, a putative low molecular mass penicillin binding protein from Mycobacterium tuberculosis H(37)Rv. Bourai N, et al. Microb Pathog, 2012 Feb. PMID 22138550
  3. Subfamily-specific adaptations in the structures of two penicillin-binding proteins from Mycobacterium tuberculosis. Prigozhin DM, et al. PLoS One, 2014. PMID 25551456, Free PMC Article
  4. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  5. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Double deletion of PknI/DacB2 leads to attenuation of Mycobacterium tuberculosis for growth and virulence.
    Title: Double deletion of PknI/DacB2 leads to attenuation of Mycobacterium tuberculosis for growth and virulence.
  2. Crystal structure of Rv2911 reveals strict conservation of core catalytic residues.
    Title: Subfamily-specific adaptations in the structures of two penicillin-binding proteins from Mycobacterium tuberculosis.
  3. The in vitro infection studies with THP-1 cells showed increased intracellular survival of dacB2 mutant compared to parent and complemented strains.
    Title: Deletion and overexpression studies on DacB2, a putative low molecular mass penicillin binding protein from Mycobacterium tuberculosis H(37)Rv.
Submit: New GeneRIF Correction

Homology

Preferred Names
penicillin-binding protein DacB2
YP_177914.1
  • D-alanyl-D-alanine carboxypeptidase (DD-peptidase) (DD-carboxypeptidase) (PBP) (DD-transpeptidase) (serine-type D-ala-D-ala carboxypeptidase) (D-amino acid hydrolase)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    3218339..3219214
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_177914.1 penicillin-binding protein DacB2 [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for YP_177914.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4MLI9
    Conserved Domains (1) summary
    COG1686
    Location:16 → 281
    DacC; D-alanyl-D-alanine carboxypeptidase [Cell wall/membrane/envelope biogenesis]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
I6Y204.1

Gene LinkOut

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