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pbpA penicillin-binding protein PbpA [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 887078, updated on 6-Oct-2023
Gene symbol
pbpA
Gene description
penicillin-binding protein PbpA
Locus tag
Rv0016c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Sequence:
NC_000962.3 (18759..20234, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene membrane protein Neighboring gene anthranilate synthase component II Neighboring gene serine/threonine-protein kinase PknB Neighboring gene serine/threonine-protein kinase PknA Neighboring gene cell division protein RodA Neighboring gene phosphoserine/threonine phosphatase PstP Neighboring gene FHA domain-containing protein FhaB

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The transpeptidase PbpA and noncanonical transglycosylase RodA of Mycobacterium tuberculosis play important roles in regulating bacterial cell lengths. Arora D, et al. J Biol Chem, 2018 Apr 27. PMID 29530985, Free PMC Article
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. results emphasize the fact that whereas redundant enzymes probably compensate for the absence of RodA or PbpA during in vitro growth, the two proteins play critical roles for the survival of the pathogen inside its host.
    Title: The transpeptidase PbpA and noncanonical transglycosylase RodA of Mycobacterium tuberculosis play important roles in regulating bacterial cell lengths.
Submit: New GeneRIF Correction

Homology

Preferred Names
penicillin-binding protein PbpA

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    18759..20234 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_214530.1 penicillin-binding protein PbpA [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_214530.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A654T784
    Conserved Domains (1) summary
    COG0768
    Location:45 → 490
    FtsI; Cell division protein FtsI/penicillin-binding protein 2 [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WKD1.1

Gene LinkOut

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Molecular Biology Databases
Research Materials