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pstP phosphoserine/threonine phosphatase PstP [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 887070, updated on 6-Oct-2023

Summary

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Gene symbol
pstP
Gene description
phosphoserine/threonine phosphatase PstP
Locus tag
Rv0018c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (21637..23181, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene anthranilate synthase component II Neighboring gene serine/threonine-protein kinase PknB Neighboring gene serine/threonine-protein kinase PknA Neighboring gene penicillin-binding protein PbpA Neighboring gene cell division protein RodA Neighboring gene FHA domain-containing protein FhaB Neighboring gene FHA domain-containing protein FhaA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Serine/Threonine Protein Phosphatase PstP of Mycobacterium tuberculosis Is Necessary for Accurate Cell Division and Survival of Pathogen. Sharma AK, et al. J Biol Chem, 2016 Nov 11. PMID 27758870, Free PMC Article
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. data suggest an important role for PstP in establishing and maintaining infection, possibly via the modulation of cell division events.
    Title: Serine/Threonine Protein Phosphatase PstP of Mycobacterium tuberculosis Is Necessary for Accurate Cell Division and Survival of Pathogen.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

General protein information

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Preferred Names
phosphoserine/threonine phosphatase PstP
NP_214532.1
  • Experimental studies have shown that PstP specifically dephosporylates model phospho-Ser/Thr substrates and it is likely that PknB (Rv0014c) and PstP may act as a functional pair in vivo to control mycobacterial cell growth.

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    21637..23181 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_214532.1 phosphoserine/threonine phosphatase PstP [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_214532.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4LTI1
    Conserved Domains (2) summary
    NF033484
    Location:13 → 228
    Stp1_PP2C_phos; Stp1/IreP family PP2C-type Ser/Thr phosphatase
    NF033761
    Location:422 → 498
    gliding_GltJ; adventurous gliding motility protein GltJ
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WHW5.1

Gene LinkOut

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Molecular Biology Databases
Research Materials