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lprA lipoprotein LprA [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 887017, updated on 26-Jun-2025
Gene symbol
lprA
Gene description
lipoprotein LprA
Locus tag
Rv1270c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Sequence:
NC_000962.3 (1419014..1419748, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene drug ABC transporter ATP-binding protein Neighboring gene drug ABC transporter ATP-binding protein

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Mycobacterium tuberculosis LprA is a lipoprotein agonist of TLR2 that regulates innate immunity and APC function. Pecora ND, et al. J Immunol, 2006 Jul 1. PMID 16785538
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. LprA is a glycosylated lipoprotein with potent Toll-like receptor 2 (TLR2) agonist activity that modulates antigen processing of dendritic cells and macrophages.
    Title: Mycobacterium tuberculosis LprA is a lipoprotein agonist of TLR2 that regulates innate immunity and APC function.
Submit: New GeneRIF Correction

Homology

Preferred Names
lipoprotein LprA

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    1419014..1419748 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_215786.1 lipoprotein LprA [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_215786.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2I7W629
    Conserved Domains (1) summary
    pfam07161
    Location:45 → 239
    LppX_LprAFG; LppX_LprAFG lipoprotein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WK55.1

Gene LinkOut

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Molecular Biology Databases