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Rv0081 HTH-type transcriptional regulator [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 887012, updated on 6-Oct-2023
Gene symbol
Rv0081
Gene description
HTH-type transcriptional regulator
Locus tag
Rv0081
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Sequence:
NC_000962.3 (89575..89919)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene oxidoreductase Neighboring gene oxidoreductase Neighboring gene formate hydrogenlyase HycD

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Structural basis of hypoxic gene regulation by the Rv0081 transcription factor of Mycobacterium tuberculosis. Kumar A, et al. FEBS Lett, 2019 May. PMID 30941756
  2. Transcription factor Rv0081 from Mycobacterium tuberculosis: purification, crystallization and initial crystallographic analysis. Dong S, et al. Acta Crystallogr F Struct Biol Commun, 2017 May 1. PMID 28471360, Free PMC Article
  3. Transcription factors Rv0081 and Rv3334 connect the early and the enduring hypoxic response of Mycobacterium tuberculosis. Sun X, et al. Virulence, 2018. PMID 30165798, Free PMC Article
  4. Components of the Rv0081-Rv0088 locus, which encodes a predicted formate hydrogenlyase complex, are coregulated by Rv0081, MprA, and DosR in Mycobacterium tuberculosis. He H, et al. J Bacteriol, 2011 Oct. PMID 21821774, Free PMC Article
  5. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Structural basis of hypoxic gene regulation by the Rv0081 transcription factor of Mycobacterium tuberculosis
    Title: Structural basis of hypoxic gene regulation by the Rv0081 transcription factor of Mycobacterium tuberculosis.
  2. Under hypoxia, Rv0081 positively regulated the expression of Rv3334 while Rv3334 repressed transcription of Rv0081. In addition, we demonstrated that Rv0081 formed dimer and bound to the promoter region of Rv3334.
    Title: Transcription factors Rv0081 and Rv3334 connect the early and the enduring hypoxic response of Mycobacterium tuberculosis.
  3. Purification, crystallization and initial crystallographic analysis of transcription factor Rv0081 from Mycobacterium tuberculosis has been reported.
    Title: Transcription factor Rv0081 from Mycobacterium tuberculosis: purification, crystallization and initial crystallographic analysis.
  4. DosR/DevR and MprA positively regulate Rv0081 expression by binding to recognition sequences that either partially or completely overlap that recognized by Rv0081, respectively.
    Title: Components of the Rv0081-Rv0088 locus, which encodes a predicted formate hydrogenlyase complex, are coregulated by Rv0081, MprA, and DosR in Mycobacterium tuberculosis.
Submit: New GeneRIF Correction

Homology

Preferred Names
HTH-type transcriptional regulator

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    89575..89919
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_214595.1 HTH-type transcriptional regulator [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_214595.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4M1K2
    Conserved Domains (1) summary
    NF033788
    Location:11 → 86
    HTH_metalloreg; metalloregulator ArsR/SmtB family transcription factor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WMI7.1

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