U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

rho transcription termination factor Rho [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 886952, updated on 20-Feb-2025
Gene symbol
rho
Gene description
transcription termination factor Rho
Locus tag
Rv1297
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
NEW
Try the new Gene table
Try the new Transcript table
Sequence:
NC_000962.3 (1453204..1455012)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene homoserine dehydrogenase Neighboring gene threonine synthase Neighboring gene homoserine kinase Neighboring gene 50S ribosomal protein L31 Neighboring gene peptide chain release factor PrfA Neighboring gene release factor glutamine methyltransferase

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Depleting Mycobacterium tuberculosis of the transcription termination factor Rho causes pervasive transcription and rapid death. Botella L, et al. Nat Commun, 2017 Mar 28. PMID 28348398, Free PMC Article
  2. ATP-dependent motor activity of the transcription termination factor Rho from Mycobacterium tuberculosis. D'Heygère F, et al. Nucleic Acids Res, 2015 Jul 13. PMID 25999346, Free PMC Article
  3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. inhibition of Rho may provide an alternative strategy to treat tuberculosis with an efficacy similar to inhibition of RNA polymerase.
    Title: Depleting Mycobacterium tuberculosis of the transcription termination factor Rho causes pervasive transcription and rapid death.
  2. Ths study demonstrates that MtbRho is a bona fide molecular motor and directional helicase which requires a catalytic site competent for ATP hydrolysis to disrupt RNA duplexes or transcription elongation complexes.
    Title: ATP-dependent motor activity of the transcription termination factor Rho from Mycobacterium tuberculosis.
Submit: New GeneRIF Correction

Homology

Preferred Names
transcription termination factor Rho

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    1453204..1455012
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_215813.1 transcription termination factor Rho [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_215813.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A655IJ69
    Conserved Domains (1) summary
    PRK12678
    Location:15 → 602
    PRK12678; transcription termination factor Rho; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WHF3.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases