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hsp heat shock protein [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 886667, updated on 6-Oct-2023

Summary

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Gene symbol
hsp
Gene description
heat shock protein
Locus tag
Rv0251c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
Also known as
acr2; hrpA; hsp20
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Genomic context

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Sequence:
NC_000962.3 (302173..302652, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene succinate dehydrogenase membrane anchor subunit Neighboring gene hypothetical protein Neighboring gene nitrite reductase large subunit NirB Neighboring gene nitrite reductase small subunit NirD

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Infection biology of a novel alpha-crystallin of Mycobacterium tuberculosis: Acr2. Wilkinson KA, et al. J Immunol, 2005 Apr 1. PMID 15778386
  2. The stress-responsive chaperone alpha-crystallin 2 is required for pathogenesis of Mycobacterium tuberculosis. Stewart GR, et al. Mol Microbiol, 2005 Feb. PMID 15686559
  3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. by its up-regulation early after entry to cells, Acr2 gives away the presence of Mycobacterium tuberculosis to the immune response
    Title: Infection biology of a novel alpha-crystallin of Mycobacterium tuberculosis: Acr2.
  2. contributes to persistent infection with M. tuberculosis
    Title: The stress-responsive chaperone alpha-crystallin 2 is required for pathogenesis of Mycobacterium tuberculosis.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
heat shock protein
NP_214765.1
  • Hsp (alternate gene name: hsp20, hrpA, acr2), heat-stress-induced ribosome-binding protein A. Belongs to the small heat shock protein (HSP20) family.

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    302173..302652 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_214765.1 heat shock protein [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_214765.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4M3C3
    Conserved Domains (1) summary
    COG0071
    Location:18 → 157
    IbpA; Molecular chaperone IbpA, HSP20 family [Posttranslational modification, protein turnover, chaperones]
Nucleotide Protein
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