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grpE stress response protein GrpE [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 886497, updated on 12-Jun-2021
Gene symbol
grpE
Gene description
stress response protein GrpE
Locus tag
Rv0351
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Sequence:
NC_000962.3 (421709..422416)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene transcriptional regulator Neighboring gene hypothetical protein Neighboring gene chaperone protein DnaK Neighboring gene chaperone protein DnaJ Neighboring gene heat shock protein transcriptional repressor HspR Neighboring gene PPE family protein PPE7

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Mycobacterium tuberculosis GrpE, A Heat-Shock Stress Responsive Chaperone, Promotes Th1-Biased T Cell Immune Response via TLR4-Mediated Activation of Dendritic Cells. Kim WS, et al. Front Cell Infect Microbiol, 2018. PMID 29637049, Free PMC Article
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Mycobacterium tuberculosis GrpE-stimulated dendritic cells induced the proliferation of GrpE-specific Th1-type effector/memory CD4(+)/CD8(+)CD44(high)CD62L(low) T cells from the spleen of Mtb-infected mice in a TLR4-dependent manner.
    Title: Mycobacterium tuberculosis GrpE, A Heat-Shock Stress Responsive Chaperone, Promotes Th1-Biased T Cell Immune Response via TLR4-Mediated Activation of Dendritic Cells.
Submit: New GeneRIF Correction

Homology

Preferred Names
stress response protein GrpE
NP_214865.1
  • HSP-70 cofactor

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    421709..422416
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_214865.1 stress response protein GrpE [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_214865.1

    Status: PROVISIONAL

    Conserved Domains (2) summary
    PRK14142
    Location:7 → 229
    PRK14142; heat shock protein GrpE; Provisional
    cd00446
    Location:56 → 106
    GrpE; 2-helical coiled coil [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WMT5.1

Gene LinkOut

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