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Rv0431 tuberculin-like peptide [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 886362, updated on 10-Feb-2026
Gene symbol
Rv0431
Gene description
tuberculin-like peptide
Locus tag
Rv0431
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Sequence:
NC_000962.3 (519073..519567)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene GCN5-like N-acetyltransferase Neighboring gene polypeptide deformylase Neighboring gene hypothetical protein Neighboring gene superoxide dismutase Neighboring gene carboxylate-amine ligase

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Mycobacterium tuberculosis Rv0431 expressed in Mycobacterium smegmatis, a potentially mannosylated protein, mediated the immune evasion of RAW 264.7 macrophages. Deng G, et al. Microb Pathog, 2016 Nov. PMID 27765619
  2. Genetic regulation of vesiculogenesis and immunomodulation in Mycobacterium tuberculosis. Rath P, et al. Proc Natl Acad Sci U S A, 2013 Dec 3. PMID 24248369, Free PMC Article
  3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. These results suggested that Rv0431, a probably mannosylated protein might promote the evasion of immune responses during mycobacterial infection.
    Title: Mycobacterium tuberculosis Rv0431 expressed in Mycobacterium smegmatis, a potentially mannosylated protein, mediated the immune evasion of RAW 264.7 macrophages.
  2. Appears to regulate mycobacterial membrane vesicles formation, and therefore we suggest it be named "vesiculogenesis and immune response regulator" (virR).
    Title: Genetic regulation of vesiculogenesis and immunomodulation in Mycobacterium tuberculosis.
Submit: New GeneRIF Correction

Homology

Preferred Names
tuberculin-like peptide

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    519073..519567
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_214945.1 tuberculin-like peptide [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_214945.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4LZ03
    Conserved Domains (1) summary
    pfam13399
    Location:79 → 163
    LytR_C; LytR cell envelope-related transcriptional attenuator
Nucleotide Protein
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